Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute generalised exanthematous pustulosis
ADR ID BADD_A04733
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.005      Acute generalised exanthematous pustulosis
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.10      Pustular conditions
23.03.10.002      Acute generalised exanthematous pustulosis
Description Rare skin eruption characterized by acute formation of pustules filled with NEUTROPHILS, fever, and peripheral blood LEUKOCYTOSIS. Most cases are associated with the use of antibiotics (e.g., BETA-LACTAMS). [MeSH]
MedDRA Code 10048799
MeSH ID D056150
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Toxic pustuloderma | Acute generalis. exematous pustul | AGEP | Acute generalised exanthematous pustulosis | Acute generalized exanthematous pustulosis | Photoinduced acute generalised exanthematous pustulosis | Photoinduced acute generalized exanthematous pustulosis | Acute localized exanthematous pustulosis | Acute localised exanthematous pustulosis | Acute Generalized Exanthematous Pustulosis | Pustulosis, Exanthematous, Acute Generalized | Acute Localized Exanthematous Pustulosis | Pustulosis, Exanthematous, Acute Localized
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00039Acyclovir0.000782%
BADD_D00076Allopurinol0.000988%
BADD_D00129Amoxicillin0.000636%
BADD_D00151Apixaban--
BADD_D00178Atenolol0.000222%
BADD_D00206Aztreonam0.000319%
BADD_D00235Benzalkonium chloride--
BADD_D00277Bisoprolol0.002013%
BADD_D00280Bleomycin0.000533%
BADD_D00312Bupropion0.000088%
BADD_D00347Candesartan cilexetil0.005782%
BADD_D00349Capecitabine--
BADD_D00356Carbamazepine0.001684%
BADD_D00382Cefazolin0.000958%
BADD_D00386Cefepime0.000639%
BADD_D00390Cefotaxime0.000532%
BADD_D00405Ceftriaxone0.316600%
BADD_D00406Ceftriaxone sodium--
BADD_D00407Cefuroxime0.000639%
BADD_D00410Celecoxib0.000919%
BADD_D00412Cephalexin0.000620%
BADD_D00417Cetirizine0.000464%
BADD_D00418Cetirizine hydrochloride--
BADD_D00471Ciprofloxacin--
BADD_D00480Clarithromycin0.006169%
BADD_D00483Clindamycin0.000269%
BADD_D00486Clindamycin palmitate hydrochloride (pediatric)--
BADD_D00501Clonazepam0.000129%
BADD_D00504Clopidogrel0.000540%
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