Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status Prescription
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9977; 0143-9569; 0143-9979; 0143-9976; 0143-9568
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.0010.000958%
Abdominal pain07.01.05.0020.003512%
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.0010.000639%Not Available
Alanine aminotransferase increased13.03.01.0030.000958%
Alcohol intolerance14.02.01.0010.000333%
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.0060.018520%
Anaphylactic shock24.06.02.004; 10.01.07.0020.014688%Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.0030.001916%Not Available
Angioedema23.04.01.001; 10.01.05.0090.009898%Not Available
Anosmia17.04.04.001; 22.04.03.0060.000639%
Anxiety19.06.02.002--
Aplastic anaemia01.03.03.002--Not Available
Arrhythmia02.03.02.001--Not Available
Arteriosclerosis coronary artery24.04.04.012; 02.02.01.0110.000250%Not Available
Arteriospasm coronary24.04.04.005; 02.02.02.0050.001916%Not Available
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.0060.001277%
Asphyxia22.02.02.001; 12.01.08.0110.000167%Not Available
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blindness17.17.01.003; 06.02.02.0010.002874%Not Available
Blister23.03.01.001; 12.01.06.0020.001916%Not Available
Blood bilirubin increased13.03.01.0080.000639%
Blood creatinine decreased13.13.01.003--Not Available
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood pressure decreased13.14.03.0020.005747%Not Available
Blood urea increased13.13.01.006--Not Available
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