Drug Name |
Ceftriaxone sodium |
Drug ID |
BADD_D00406 |
Description |
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic.[A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627]. Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for the convenience of daily or twice-daily dosing.[A215582] |
Indications and Usage |
For the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph |
Marketing Status |
Prescription; Discontinued |
ATC Code |
J01DD04 |
DrugBank ID |
DB01212
|
KEGG ID |
D00924
|
MeSH ID |
D002443
|
PubChem ID |
9570985
|
TTD Drug ID |
D07ACT
|
NDC Product Code |
50090-2444; 60505-6151; 50090-0944; 0409-7338; 0409-7335; 50090-3810; 67184-1007; 67184-1006; 50090-4978; 25021-108; 70518-3099; 50090-3838; 38779-2383; 0409-7332; 0781-3209; 71205-545; 67184-1008; 0409-7334; 60505-6152; 70518-2499; 70518-0168; 68071-4682; 50090-3447; 0781-3210; 67184-1005; 0781-3206; 0338-5003; 0781-3207; 0338-5002; 70518-2301; 50090-1875; 0409-7333; 60505-6149; 0781-3208; 0409-7337; 51065-004; 50090-4689; 0409-7336; 60505-6150; 60505-6148; 66288-6100 |
Synonyms |
Ceftriaxone | Ceftriaxon | Cefatriaxone | Ceftriaxone, Disodium Salt, Hemiheptahydrate | Ceftrex | Ceftriaxon Curamed | Ceftriaxon Hexal | Ceftriaxona Andreu | Ceftriaxona LDP Torlan | Ceftriaxone Irex | Ceftriaxone Sodium | Ceftriaxone Sodium, Anhydrous | Anhydrous Ceftriaxone Sodium | Lendacin | Longacef | Longaceph | Ro13-9904 | Ro13 9904 | Ro139904 | Ro-13-9904 | Ro 13-9904 | Ro 13 9904 | Ro 139904 | Rocephin | Rocefalin | Rocephine | Rocefin | Tacex | Terbac | Ceftriaxone, Disodium Salt | Benaxona | Cefaxona |