Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Adverse drug reaction
ADR Hierarchy
08      General disorders and administration site conditions
08.06      Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01      Therapeutic and nontherapeutic responses      Adverse drug reaction
Description Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. [MeSH]
MedDRA Code 10061623
MeSH ID D064420; D064420; D064420
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Adverse drug reaction NOS | Adverse drug reaction | Drug side effect | Drug-Related Side Effects and Adverse Reactions | Drug Related Side Effects and Adverse Reactions | Side Effects of Drugs | Drug Side Effects | Drug Side Effect | Effects, Drug Side | Side Effect, Drug | Side Effects, Drug | Adverse Drug Reaction | Adverse Drug Reactions | Drug Reaction, Adverse | Drug Reactions, Adverse | Reactions, Adverse Drug | Adverse Drug Event | Adverse Drug Events | Drug Event, Adverse | Drug Events, Adverse | Drug Toxicity | Toxicity, Drug | Drug Toxicities | Toxicities, Drug
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Alanine aminotransferase 1P24298Not Available
Alkaline phosphatase, placental typeP05187Not Available
ATP-binding cassette sub-family C member 9Q63563Not Available
Brain-derived neurotrophic factorP21237Not Available
Brain-derived neurotrophic factorP23560T93122
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1Q9UHR4Not Available
Cocaine esteraseO00748Not Available
Cytochrome P450 1A2P05177Not Available
Cytochrome P450 2B1P00176Not Available
Cytochrome P450 2B6P20813T11793
Cytochrome P450 2C19P33261Not Available
Cytochrome P450 2D6P10635T57392
Cytochrome P450 2E1P05181Not Available
Cytochrome P450 3A4P08684T37848
Delta-type opioid receptorP41143T58992
Erythroagglutinating phytohemagglutininP05088Not Available
G protein-activated inward rectifier potassium channel 1P48549T38012
Gamma-tubulin complex component 3Q96CW5Not Available
Glial fibrillary acidic proteinP14136Not Available
Inosine triphosphate pyrophosphataseQ9BY32Not Available
Kappa-type opioid receptorP41145T60693
Methionine aminopeptidase 1P53582T42337
Muscarinic acetylcholine receptorQ53XZ3Not Available
Nuclear receptor subfamily 4 group A member 3Q92570T93949
Parathyroid hormone/parathyroid hormone-related peptide receptorQ03431T67710
Poly(A) polymerase alphaP25500Not Available
Prostacyclin synthaseQ16647T83979
Prostaglandin G/H synthase 1P23219T60529
Protein c-FosP01100T28025
S-adenosylhomocysteine hydrolase-like protein 1O43865Not Available
Solute carrier family 2, facilitated glucose transporter member 1P11166T89458
Solute carrier family 2, facilitated glucose transporter member 2P11168Not Available
T-cell surface glycoprotein CD3 epsilon chainA6H6M1Not Available
Thiopurine S-methyltransferaseP51580Not Available
Tumor necrosis factorP01375T20178
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00205Azithromycin monohydrate--
BADD_D00314Bupropion hydrochloride--
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