Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ascorbic acid
Drug ID BADD_D00171
Description A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Indications and Usage Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
Marketing Status approved; nutraceutical
ATC Code G01AD03; S01XA15
DrugBank ID DB00126
KEGG ID D00018
MeSH ID D001205
PubChem ID 54670067
TTD Drug ID D07AHW
NDC Product Code 63083-1505; 67157-101; 72783-1001; 63238-3000; 51552-0164; 49452-0742; 10695-126; 62512-0020; 51927-5098
UNII PQ6CK8PD0R
Synonyms Ascorbic Acid | Acid, Ascorbic | L-Ascorbic Acid | Acid, L-Ascorbic | L Ascorbic Acid | Vitamin C | Hybrin | Magnorbin | Sodium Ascorbate | Ascorbate, Sodium | Ascorbic Acid, Monosodium Salt | Ferrous Ascorbate | Ascorbate, Ferrous | Magnesium Ascorbate | Ascorbate, Magnesium | Magnesium di-L-Ascorbate | Magnesium di L Ascorbate | di-L-Ascorbate, Magnesium | Magnesium Ascorbicum
Chemical Information
Molecular Formula C6H8O6
CAS Registry Number 50-81-7
SMILES C(C(C1C(=C(C(=O)O1)O)O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.000991%
Abdominal pain07.01.05.0020.002330%
Abdominal pain upper07.01.05.0030.000496%
Acute myocardial infarction02.02.02.001; 24.04.04.0010.000991%Not Available
Agitation19.06.02.001; 17.02.05.012--
Amnesia19.20.01.001; 17.03.02.0010.000496%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.000496%
Anaphylactic shock24.06.02.004; 10.01.07.0020.001586%Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Anhedonia19.15.02.0070.000991%Not Available
Anxiety19.06.02.0020.003073%
Application site reaction12.07.01.006; 08.02.01.006--Not Available
Arrhythmia02.03.02.0010.000496%Not Available
Arthralgia15.01.02.001--
Arthropathy15.01.01.003--Not Available
Asthenia08.01.01.0010.001487%Not Available
Atrial fibrillation02.03.03.0020.000496%
Back pain15.03.04.0050.002330%
Blood pressure fluctuation24.06.01.0020.001685%Not Available
Cardiac arrest02.03.04.0010.000496%
Cardiogenic shock02.05.01.003; 24.06.02.0060.000496%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.0070.000496%
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.0090.001239%Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.12.02.0030.000743%Not Available
Chills15.05.03.016; 08.01.09.0010.005254%
Cholecystitis acute09.03.01.0030.000743%Not Available
Cholecystitis chronic09.03.01.0040.001239%Not Available
Cholelithiasis09.03.01.0020.000991%Not Available
Chromaturia20.02.01.0020.000496%
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