Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.001422%
Abdominal pain07.01.05.0020.003657%
Abdominal pain upper07.01.05.003--
Abdominal tenderness07.01.05.0040.000406%Not Available
Abscess11.01.08.0010.000813%Not Available
Acne23.02.01.001--Not Available
Acute febrile neutrophilic dermatosis23.03.03.033; 01.02.01.0060.000813%Not Available
Acute psychosis19.03.01.0010.000609%Not Available
Adrenal insufficiency05.01.02.001; 14.11.01.0040.001422%
Adrenal suppression14.11.01.005; 05.01.02.0020.000106%Not Available
Adrenocortical insufficiency acute14.11.01.020; 05.01.02.0050.001422%Not Available
Agitation19.06.02.001; 17.02.05.0120.001219%
Alopecia23.02.02.001--
Amnesia19.20.01.001; 17.03.02.0010.001016%
Anaemia01.03.02.001--
Anal fistula07.11.05.0020.000813%
Anaphylactic reaction10.01.07.001; 24.06.03.0060.001016%
Anaphylactic shock24.06.02.004; 10.01.07.0020.000609%Not Available
Anger19.04.02.0010.000406%Not Available
Angioedema23.04.01.001; 10.01.05.0090.001625%Not Available
Anorectal disorder07.03.01.001--Not Available
Anosmia22.04.03.006; 17.04.04.001--
Anxiety19.06.02.002--
Aphasia19.21.01.001; 17.02.03.0010.000406%
Aphonia22.02.05.024; 19.19.01.002; 17.02.08.0090.000406%
Aphthous ulcer07.05.06.0020.000406%Not Available
Arrhythmia02.03.02.0010.000609%Not Available
Arthralgia15.01.02.0010.002031%
Arthritis15.01.01.001--
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