Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Brivaracetam
Drug ID BADD_D00297
Description Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184]. It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 [L760].
Indications and Usage Used as adjunctive therapy for partial-onset seizures in patients 16 years of age or older.
Marketing Status Prescription
ATC Code N03AX23
DrugBank ID DB05541
KEGG ID D08879
MeSH ID C482793
PubChem ID 9837243
TTD Drug ID D0CT4D
NDC Product Code 52076-6268; 50474-470; 69037-0055; 50474-370; 50474-870; 50474-670; 50474-770; 50474-570; 50474-970; 71666-007; 82608-003; 36998-0118; 69766-031; 16812-009
Synonyms brivaracetam | 2-(2-oxo-4-propylpyrrolidin-1-yl)butanamide | (2S)-2-((4R)-2-oxo-4-propylpyrrolidin-1-yl)butanamide | 1-pyrrolidineacetamide, alpha-ethyl-2-oxo-4-propyl-, (alphaS,4R)- | UCB 34714 | UCB34714 | UCB-34714 | Briviact
Chemical Information
Molecular Formula C11H20N2O2
CAS Registry Number 357336-20-0
SMILES CCCC1CC(=O)N(C1)C(CC)C(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abortion spontaneous18.01.04.0010.000338%Not Available
Acute psychosis19.03.01.0010.000338%Not Available
Affective disorder19.04.04.0010.000845%Not Available
Aggression19.05.01.0010.002028%Not Available
Agitation17.02.05.012; 19.06.02.0010.000845%
Alopecia23.02.02.0010.000507%
Anger19.04.02.0010.000845%Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.0020.002197%
Apathy19.04.04.002--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Aura17.02.07.0110.000507%Not Available
Back pain15.03.04.005--
Belligerence19.05.01.015--Not Available
Bronchospasm22.03.01.004; 10.01.03.0120.000338%
Cardiac arrest02.03.04.0010.000132%
Confusional state19.13.01.001; 17.02.03.0050.001014%
Coordination abnormal17.02.02.004--Not Available
Cough22.02.03.0010.000507%
Death08.04.01.001--
Delirium19.13.02.0010.000507%
Depressed mood19.15.02.001--Not Available
Depression19.15.01.0010.002028%
Disorientation19.13.01.002; 17.02.05.0150.000338%Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.0030.002535%
Epilepsy17.12.03.0020.000676%Not Available
Euphoric mood19.04.02.0060.000338%
Fatigue08.01.01.002--
Gait disturbance17.02.05.016; 08.01.02.002--
The 1th Page    1 2 3    Next   Last    Total 3 Pages