| ADR Ontology |
| ADR Term |
Serum sickness |
| ADR ID |
BADD_A03979 |
| ADR Hierarchy |
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| Description |
A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. [CTCAE] Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses. [MeSH] |
| MedDRA Code |
10040400 |
| MeSH ID |
D012713
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Synonym |
| Anaphylactic shock due to serum, not elsewhere classified | Other serum reaction, not elsewhere classified | Serum reaction | Serum sickness | Serum Sickness | Serum Sicknesses | Sickness, Serum | Sicknesses, Serum |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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