Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefaclor
Drug ID BADD_D00378
Description Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Indications and Usage For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.
Marketing Status Prescription; Discontinued
ATC Code J01DC04
DrugBank ID DB00833
KEGG ID D00256
MeSH ID D002433
PubChem ID 51039
NDC Product Code 0093-1087; 0143-9985; 61442-172; 63629-1007; 23594-375; 61442-171; 23594-250; 0143-9986; 50090-1602; 23594-125
Synonyms Cefaclor | Cefaclor Anhydrous | Keclor | 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))- | S-6472 | S 6472 | S6472 | Ceclor | Cefaclor Monohydrate | Lilly 99638
Chemical Information
Molecular Formula C15H14ClN3O4S
CAS Registry Number 53994-73-3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.01.0030.000319%
Anaphylactic reaction24.06.03.006;
Anaphylactic shock24.06.02.004; Available
Anaphylactoid reaction24.06.03.007; Available
Angioedema10.01.05.009; Available
Aplastic anaemia01.03.03.002--Not Available
Aspartate aminotransferase increased13.03.01.0060.000319%
Asthenia08.01.01.001--Not Available
Asthma10.01.03.010; Available
Autoimmune hepatitis10.04.09.001; Available
Back pain15.03.04.005--
Blood albumin decreased13.09.01.001--Not Available
Blood bilirubin increased13.03.01.008--
Blood calcium decreased13.11.01.002--Not Available
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood potassium increased13.11.01.011--Not Available
Blood sodium decreased13.11.01.012--Not Available
Blood sodium increased13.11.01.013--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Cardiac failure congestive02.05.01.002--Not Available
Chest pain08.01.08.002;; Available
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