Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefprozil
Drug ID BADD_D00397
Description Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Indications and Usage For the treatment of the following infections (respiratory, skin, soft tissue, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph
Marketing Status Prescription; Discontinued
ATC Code J01DC10
DrugBank ID DB01150
KEGG ID D00261
MeSH ID C052018
PubChem ID 5281006
TTD Drug ID D0YX4S
NDC Product Code 68180-401; 16714-399; 16714-398; 68180-402; 61788-4000; 0093-1077; 16714-396; 65862-069; 65862-068; 57297-400; 16714-397; 67296-1180; 68180-404; 68180-403; 65862-099; 50090-1188; 65862-100; 57237-037; 57237-035; 50090-1739; 57237-036; 57237-034; 50090-1710; 65862-378; 0093-1078
Synonyms cefprozil | BMY 28100 | BMY-28100 | 7-(2-amino-2-(p-hydroxyphenyl)acetamido)-8-oxo-3-(1-propenyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid | cefprozil monohydrate | 7-(2-amino-2-(4-hydroxyphenyl)acetamido)-3-(propenyl)-3-cephem-4-carboxylic acid monohydrate | Cefzil | Procef | Arzimol | Brisoral
Chemical Information
Molecular Formula C18H19N3O5S
CAS Registry Number 92676-86-3
SMILES CC=CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acute sinusitis22.07.03.013; 11.01.13.012--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase13.03.01.031--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Aplastic anaemia01.03.03.002--Not Available
Aspartate aminotransferase increased13.03.01.006--
Blood alkaline phosphatase13.04.02.010--Not Available
Blood creatinine13.13.01.020--Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Colitis07.08.01.001--
Confusional state19.13.01.001; 17.02.03.005--
Congenital anomaly03.02.01.001--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis diaper23.03.04.005--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Developmental delay08.01.03.037--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
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