Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefdinir
Drug ID BADD_D00384
Description Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.[A180739] Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes.[A180724,A180727]
Indications and Usage For the treatment of the respiratory, skin, soft tissue, and ENT infections caused by H. influenzae (including b-lactamase producing strains), H. parainfluenzae (including b-lactamase producing strains), S. pneumoniae (penicillin-susceptible strains), S. pyogenes, S. aureus (including b-lactamase producing strains), and M. catarrhalis.
Marketing Status Prescription; Discontinued
ATC Code J01DD15
DrugBank ID DB00535
KEGG ID D00917
MeSH ID D000077525
PubChem ID 6915944
TTD Drug ID D0WS1X
NDC Product Code 70518-2537; 71205-576; 67296-1216; 72189-043; 72189-308; 68180-711; 67877-547; 67296-0765; 67296-0469; 68071-5145; 50090-1031; 67877-548; 0781-6078; 68071-2564; 50090-3724; 63629-8969; 68788-7478; 0093-4136; 71205-380; 71205-224; 68180-722; 65862-384; 50090-2719; 61788-2000; 68001-362; 68788-7844; 68071-1788; 65862-177; 68071-4946; 72189-186; 70934-164; 71205-405; 68071-4792; 68071-3295; 63187-835; 63187-616; 72789-054; 72189-042; 16714-393; 68071-4419; 68788-8115; 50090-1029; 67877-543; 68788-7987; 72189-185; 72789-061; 68071-2599; 63187-989; 50090-1034; 0093-3160; 68071-2493; 50090-1027; 68071-1645; 43063-964; 68788-7339; 68071-2503; 61919-840; 68071-2401; 0093-4137; 71205-183; 70934-343; 68071-5106; 16714-392; 65862-219; 50090-5583; 68180-723; 68071-4856; 0781-6077; 50090-5811; 68071-4007; 53002-1526; 50090-1033; 67296-0868; 65862-218; 0781-2176; 16714-391; 50090-3723; 72189-259; 70934-062; 50090-2735; 57237-099; 68071-4970; 68788-8062; 43063-959; 70934-044
Synonyms Cefdinir | FK 482 | FK-482 | FK482 | PD 134393 | PD-134393 | 7-(2 (2-Aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid | CI 983 | CI-983 | CI983 | Omnicef
Chemical Information
Molecular Formula C14H13N5O5S2
CAS Registry Number 91832-40-5
SMILES C=CC1=C(N2C(C(C2=O)NC(=O)C(=NO)C3=CSC(=N3)N)SC1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal faeces07.01.03.001--Not Available
Acute respiratory failure22.02.06.001; 14.01.04.004--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Amylase increased13.05.01.009--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Aplastic anaemia01.03.03.002--Not Available
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Blood urine13.13.02.011--Not Available
Body temperature increased13.15.01.001--Not Available
Cardiac failure02.05.01.001--
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Choking sensation22.02.05.002; 19.01.02.002--Not Available
Cholestasis09.01.01.001--Not Available
Coagulopathy01.01.02.001--Not Available
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis diaper23.03.04.005--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.002--Not Available
Disability26.01.01.003--Not Available
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
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