Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate
Drug ID BADD_D00004
Description A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Indications and Usage For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis.
Marketing Status Prescription; Discontinued
ATC Code M01AB03; M02AA21
DrugBank ID DB00500
KEGG ID D00158
MeSH ID D014046
PubChem ID 5508
TTD Drug ID D09BHB
NDC Product Code Not Available
Synonyms Tolmetin | Tolectin | Tolmetin Sodium, Anhydrous | Anhydrous Tolmetin Sodium | Tolmetin Sodium Anhydrous | Anhydrous, Tolmetin Sodium | Sodium Anhydrous, Tolmetin | McN-2559 | McN 2559 | McN2559 | Tolmetin Sodium | Sodium, Tolmetin | Tolmetin Sodium, Dihydrate | Dihydrate Tolmetin Sodium
Chemical Information
Molecular Formula C15H14NO3-
CAS Registry Number 26171-23-3
SMILES CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Asthenia08.01.01.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Cardiac failure congestive02.05.01.002--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Flatulence07.01.04.002--
Gastritis07.08.02.001--
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Glossitis07.14.01.001--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Nausea07.01.07.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
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