Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Osteoarthritis
ADR ID BADD_A03214
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.04      Osteoarthropathies
15.01.04.001      Osteoarthritis
Description A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. [MeSH]
MedDRA Code 10031161
MeSH ID D010003; D007592; D010003; D010003; D020370; D010003; D010003; D010003; D015207
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ankle osteoarthritis | Arthrosis | Arthrosis multiple | Arthrosis NOS | Degenerative arthritis peripheral joint | DIP OA | Dysarthrosis | Elbow osteoarthritis | Finger osteoarthritis | Foot osteoarthritis | Generalised OA | Generalized osteoarthritis | Hand osteoarthritis | Hips osteoarthritis | Kaschin-Beck disease | Kaschin-Beck disease involving ankle and foot | Kaschin-Beck disease involving forearm | Kaschin-Beck disease involving hand | Kaschin-Beck disease involving lower leg | Kaschin-Beck disease involving multiple sites | Kaschin-Beck disease involving other specified sites | Kaschin-Beck disease involving pelvic region and thigh | Kaschin-Beck disease involving shoulder region | Kaschin-Beck disease involving upper arm | Kaschin-Beck disease, site unspecified | Knee osteoarthritis | Localised osteoarthritis | O/A | OA | OA hip | OA hips | OA knee | OA toes | Osteo arthritis knees | Osteo arthritis shoulders | Osteoarthritis | Osteoarthritis aggravated | Osteoarthritis deformans endemica | Osteoarthritis generalised | Osteoarthritis knee | Osteoarthritis knees | Osteoarthritis NOS | Osteoarthritis shoulders | Osteoarthrosis | Osteoarthrosis and allied disorders | Osteoarthrosis involving more than one site, but not spec as generalized, and involving unspec site | Osteoarthrosis involving or with mention of more than one site, but not specified as generalized | Osteoarthrosis involving or with mention of more than one site, but not specified as generalized, an | Osteoarthrosis involving or with mention of multiple sites, but not specified as generalized | Osteoarthrosis, generalized | Osteoarthrosis, generalized, involving hand | Osteoarthrosis, generalized, involving multiple sites | Osteoarthrosis, generalized, involving unspecified site | Osteoarthrosis, localized, not spec whether primary or secondary, involving oth spec sites | Osteoarthrosis, localized, not spec whether primary or secondary, involving pelvic region and thigh | Osteoarthrosis, localized, not specified whether primary or secondary | Osteoarthrosis, localized, not specified whether primary or secondary, involving ankle and foot | Osteoarthrosis, localized, not specified whether primary or secondary, involving forearm | Osteoarthrosis, localized, not specified whether primary or secondary, involving hand | Osteoarthrosis, localized, not specified whether primary or secondary, involving lower leg | Osteoarthrosis, localized, not specified whether primary or secondary, involving other specified sit | Osteoarthrosis, localized, not specified whether primary or secondary, involving pelvic region and t | Osteoarthrosis, localized, not specified whether primary or secondary, involving shoulder region | Osteoarthrosis, localized, not specified whether primary or secondary, involving unspecified site | Osteoarthrosis, localized, not specified whether primary or secondary, involving upper arm | Osteoarthrosis, localized, primary | Osteoarthrosis, localized, primary, involving ankle and foot | Osteoarthrosis, localized, primary, involving forearm | Osteoarthrosis, localized, primary, involving hand | Osteoarthrosis, localized, primary, involving lower leg | Osteoarthrosis, localized, primary, involving other specified sites | Osteoarthrosis, localized, primary, involving pelvic region and thigh | Osteoarthrosis, localized, primary, involving shoulder region | Osteoarthrosis, localized, primary, involving unspecified site | Osteoarthrosis, localized, primary, involving upper arm | Osteoarthrosis, localized, secondary | Osteoarthrosis, localized, secondary, involving ankle and foot | Osteoarthrosis, localized, secondary, involving forearm | Osteoarthrosis, localized, secondary, involving hand | Osteoarthrosis, localized, secondary, involving lower leg | Osteoarthrosis, localized, secondary, involving other specified sites | Osteoarthrosis, localized, secondary, involving pelvic region and thigh
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin--
BADD_D00037Aclidinium bromide--
BADD_D00039Acyclovir--
BADD_D00047Afatinib--
BADD_D00066Alendronic acid0.044860%
BADD_D00069Alfuzosin--
BADD_D00085Alprazolam--
BADD_D00097Amantadine--
BADD_D00118Amitriptyline--
BADD_D00121Amlodipine0.000031%
BADD_D00122Amlodipine besylate--
BADD_D00139Anagrelide--
BADD_D00142Anastrozole0.000754%
BADD_D00151Apixaban--
BADD_D00156Apremilast--
BADD_D00157Aprepitant--
BADD_D00165Aripiprazole--
BADD_D00172Asenapine--
BADD_D00189Atropine--
BADD_D00194Azacitidine--
BADD_D00195Azathioprine0.001436%
BADD_D00209Baclofen--
BADD_D00260Betamethasone--
BADD_D00263Betaxolol--
BADD_D00269Bexarotene--
BADD_D00277Bisoprolol--
BADD_D00284Bortezomib--
BADD_D00285Bosentan--
BADD_D00294Brimonidine--
BADD_D00308Bupivacaine--
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