Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Atropine
Drug ID BADD_D00189
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D00113
MeSH ID D001285
PubChem ID 174174
NDC Product Code 69205-034; 60592-049; 11704-105; 63827-1015; 13371-488; 12714-034; 11704-106; 64181-0048; 11704-107; 11704-101; 11704-104
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C17H23NO3
CAS Registry Number 51-55-8
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Atrial fibrillationNot AvailableF1PE02Not Available25748673
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Accommodation disorder06.02.04.001--Not Available
Anaphylactic shock10.01.07.002; Available
Angina pectoris24.04.04.002;
Angioedema23.04.01.001; Available
Angle closure glaucoma06.03.01.001--Not Available
Anhidrosis23.02.03.001--Not Available
Anticholinergic syndrome17.05.01.0010.002747%Not Available
Arrhythmia supraventricular02.03.03.001--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Blepharitis23.03.04.012; Available
Blindness06.02.02.001; Available
Blood pressure increased13.14.03.005--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.0020.000687%Not Available
Cardiac arrest02.03.04.0010.000179%
Cerebellar syndrome17.02.02.002--Not Available
Chest pain08.01.08.002;; Available
Choroidal detachment12.01.04.006; Available
Clonus17.02.05.002--Not Available
Coma17.02.09.001--Not Available
Confusional state19.13.01.001;
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