Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Betamethasone
Drug ID BADD_D00260
Description Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.[A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.[A192444]
Indications and Usage Systemic use: for the treatment of edocrine disorders, rheumatic disorders, collagen diseases, dermatological diseases, allergic states, ophthalmic diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, gastrointestinal diseases, tuberculous meningitis and trichinosis.
Marketing Status Discontinued
ATC Code A07EA04; C05AA05; D07AC01; D07XC01; H02AB01; R01AD06; R03BA04; S01BA06; S01CB04; S02BA07; S03BA03
DrugBank ID DB00443
KEGG ID D00244
MeSH ID D001623
PubChem ID 9782
NDC Product Code 52128-166; 22552-0030; 64958-0012
Synonyms Betamethasone | Flubenisolone | Betadexamethasone | Celestona | Cellestoderm | Celeston | Celestone
Chemical Information
Molecular Formula C22H29FO5
CAS Registry Number 378-44-9
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abscess11.01.08.001--Not Available
Acne23.02.01.001--Not Available
Alkalosis hypokalaemic14.01.02.002--Not Available
Anaphylactic reaction24.06.03.006;
Anaphylactic shock24.06.02.004; Available
Anaphylactoid reaction24.06.03.007; Available
Angioedema10.01.05.009; Available
Arrhythmia02.03.02.001--Not Available
Arthropathy15.01.01.003--Not Available
Atrophy08.03.04.001--Not Available
Benign intracranial hypertension17.07.02.001--Not Available
Blindness06.02.02.001; Available
Bone pain15.02.01.0010.000594%
Bradycardia02.03.02.002--Not Available
Calcinosis08.03.04.002--Not Available
Carbohydrate tolerance decreased13.02.02.003--Not Available
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002--Not Available
Cardiomegaly02.04.02.001--Not Available
Cataract subcapsular06.06.01.002--Not Available
Circulatory collapse24.06.02.001--Not Available
Cushing's syndrome19.07.03.002;;; Available
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
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