Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute kidney injury
ADR ID BADD_A06560
ADR Hierarchy
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.016      Acute kidney injury
Description A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). [CTCAE] Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | Conditions in which the function of KIDNEYS deteriorates suddenly in a matter of days or even hours. It is characterized by the sudden drop in GLOMERULAR FILTRATION RATE. [MeSH]
MedDRA Code 10069339
MeSH ID D058186; D058186; D058186
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute kidney failure | Acute on chronic renal failure | Acute prerenal failure | Acute renal failure | Acute renal failure following labor and delivery | Acute renal failure following labor and delivery, postpartum condition or complication | Acute renal failure following labor and delivery, unspecified as to episode of care | Acute renal failure following labour and delivery | Acute renal failure with delivery, with mention of postpartum complication | Acute renal failure with lesion of renal cortical necrosis | Acute renal failure with lesion of renal medullary (papillary) necrosis | Acute renal failure with lesion of tubular necrosis | Acute renal failure with other specified pathological lesion in kidney | Acute renal failure, unspecified | ARF | Azotemia prerenal | Failure kidney acute | Kidney failure acute | Renal failure acute | Renal failure acute hypotensive | Renal failure acute ischaemic | Renal failure acute ischemic | Renal failure acute on chronic | Renal failure acute uratic | Renal shutdown acute | Shutdown renal | Acute renal insufficiency | Rhabdomyolysis-induced renal failure | Azotaemia prerenal | Acute oliguric renal failure | Acute kidney injury | Stage 1 acute kidney injury | Stage 2 acute kidney injury | Stage 3 acute kidney injury | Acute nonoliguric renal failure | Acute prerenal insufficiency | Acute Kidney Injury | Acute Kidney Injuries | Kidney Injuries, Acute | Kidney Injury, Acute | Acute Renal Injury | Acute Renal Injuries | Renal Injuries, Acute | Renal Injury, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiencies | Renal Insufficiencies, Acute | Acute Renal Insufficiency | Kidney Insufficiency, Acute | Acute Kidney Insufficiencies | Kidney Insufficiencies, Acute | Acute Kidney Insufficiency | Kidney Failure, Acute | Acute Kidney Failures | Kidney Failures, Acute | Acute Renal Failure | Acute Renal Failures | Renal Failures, Acute | Renal Failure, Acute | Acute Kidney Failure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00016Acamprosate--
BADD_D00017Acamprosate calcium--
BADD_D00023Acetaminophen0.000304%
BADD_D00029Acetyl sulfisoxazole--
BADD_D00033Acetylsalicylic acid0.000254%
BADD_D00039Acyclovir0.004312%
BADD_D00047Afatinib0.002127%
BADD_D00052Albendazole0.001691%
BADD_D00062Aldesleukin--
BADD_D00066Alendronic acid0.000881%
BADD_D00073Aliskiren0.002742%
BADD_D00076Allopurinol--
BADD_D00085Alprazolam0.000612%
BADD_D00097Amantadine--
BADD_D00103Amikacin0.000844%
BADD_D00106Aminocaproic acid0.000457%
BADD_D00115Amiodarone0.001616%
BADD_D00116Amiodarone hydrochloride--
BADD_D00121Amlodipine0.000128%
BADD_D00129Amoxicillin0.000448%
BADD_D00130Amphetamine0.000321%
BADD_D00132Amphotericin b0.000958%
BADD_D00133Ampicillin0.000505%
BADD_D00142Anastrozole0.001509%
BADD_D00151Apixaban--
BADD_D00158Aprotinin (bovine)--
BADD_D00161Argatroban0.000123%
BADD_D00169Arsenic trioxide0.000336%
BADD_D00171Ascorbic acid0.003470%
BADD_D00176Atazanavir0.003006%
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