Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Albendazole
Drug ID BADD_D00052
Description A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Indications and Usage For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Marketing Status Prescription; Discontinued
ATC Code P02CA03
DrugBank ID DB00518
KEGG ID D00134
MeSH ID D015766
PubChem ID 2082
TTD Drug ID D00KVO
NDC Product Code 73309-129; 49452-0003; 63629-1221; 43598-452; 70771-1103; 72205-051; 70710-1021; 16714-907; 42799-110; 31722-935; 69539-151; 69097-237; 72643-008; 0591-2712; 72969-104; 51927-1763; 82195-300; 52286-5500; 51407-258; 64896-693; 0115-1701; 52286-0001; 51927-0068; 60592-002; 69766-026; 53104-7736; 86055-0004; 42291-093; 78482-110
Synonyms Albendazole | Lurdex | Bilutac | Metiazol | Andazol | Albenza | Zentel | Albendoral | Albendazole Monohydrochloride | Monohydrochloride, Albendazole | Bendapar | Digezanol | Disthelm | Mediamix V Disthelm | Endoplus | Eskazole | Gascop | SK&F-62979 | SK&F 62979 | SK&F62979 | SKF-62979 | SKF 62979 | SKF62979 | Valbazen
Chemical Information
Molecular Formula C12H15N3O2S
CAS Registry Number 54965-21-8
SMILES CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.007503%Not Available
Abdominal pain07.01.05.0020.030011%
Abdominal pain upper07.01.05.0030.011254%
Abortion spontaneous18.01.04.0010.018757%Not Available
Acute hepatic failure09.01.03.0010.001957%Not Available
Agitation17.02.05.012; 19.06.02.0010.007503%
Agranulocytosis01.02.03.0010.007503%Not Available
Alopecia23.02.02.0010.022508%
Altered state of consciousness19.07.01.003; 17.02.04.0010.007503%Not Available
Anaemia01.03.02.0010.018757%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.007503%
Aphasia19.21.01.001; 17.02.03.0010.007503%
Aplastic anaemia01.03.03.002--Not Available
Arthralgia15.01.02.0010.018757%
Asthenia08.01.01.0010.093785%Not Available
Autoimmune hepatitis10.04.09.001; 09.01.07.0190.007503%Not Available
Body temperature increased13.15.01.001--Not Available
Chills08.01.09.001; 15.05.03.0160.007503%
Cholestasis09.01.01.0010.011254%Not Available
Coma17.02.09.0010.033762%Not Available
Confusional state19.13.01.001; 17.02.03.0050.007503%
Conjunctival haemorrhage24.07.05.001; 06.07.01.0010.026260%Not Available
Death08.04.01.001--
Depressed level of consciousness17.02.04.0020.018757%
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.0010.052519%
Discomfort08.01.08.0030.007503%Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.018757%
Dyspnoea22.02.01.004; 02.01.03.0020.018757%
Encephalopathy17.13.02.0010.030011%
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