Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cataract
ADR ID BADD_A00809
ADR Hierarchy
06      Eye disorders
06.06      Anterior eye structural change, deposit and degeneration
06.06.01      Cataract conditions
06.06.01.001      Cataract
Description A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. [CTCAE] Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) [MeSH]
MedDRA Code 10007739
MeSH ID D002386; D002386; D002386; D002386; D058442
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Bilateral cataracts | Cataract | Cataract (left) | Cataract (right) | Cataract aggravated | Cataract associated with other disorders | Cataract associated with other syndromes | Cataract bilateral NOS | Cataract in degenerative ocular disorders | Cataract in inflammatory ocular disorders | Cataract lenticular | Cataract NEC | Cataract NOS | Cataract NOS aggravated | Cataract secondary to glaucomatous flecks (subcapsular) | Cataract secondary to ocular disorders | Cataract specified | Cataract unilateral | Cataract unspecified | Cataract with ocular neovascularization | Cataracta complicata, unspecified | Cataracts | Cataracts lenticular | Cortical, lamellar, or zonular nonsenile cataract | Hypermature cataract | Incipient senile cataract | Infantile, juvenile, and presenile cataract | Left cataract | Myotonic cataract | Nonsenile cataract, unspecified | Other and combined forms of nonsenile cataract | Other and combined forms of senile cataract | Other cataract | Right cataract | Secondary cataract | Senile cataract | Senile cataract, unspecified | Tetanic cataract | Total or mature cataract | Unspecified cataract | Phacosclerosis | Cataract with ocular neovascularisation | Non-senile cataract, unspecified | Cataract steroid-induced | Intumescent cataract | Lens Opacities | Lens Opacity | Opacities, Lens | Opacity, Lens | Cataract, Membranous | Cataracts, Membranous | Membranous Cataract | Membranous Cataracts | Pseudoaphakia | Pseudoaphakias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
3-hydroxy-3-methylglutaryl-coenzyme A reductaseP04035T53585
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone--
BADD_D00036Acitretin0.008592%
BADD_D00041Adalimumab--
BADD_D00047Afatinib--
BADD_D00048Aflibercept--
BADD_D00051Airduo respiclick--
BADD_D00066Alendronic acid0.011215%
BADD_D00076Allopurinol--
BADD_D00079Alogliptin0.000200%
BADD_D00100Ambrisentan--
BADD_D00115Amiodarone0.005953%
BADD_D00121Amlodipine0.000046%
BADD_D00142Anastrozole0.001508%
BADD_D00151Apixaban0.008479%
BADD_D00156Apremilast--
BADD_D00165Aripiprazole--
BADD_D00178Atenolol0.000148%
BADD_D00193Axitinib--
BADD_D00194Azacitidine--
BADD_D00195Azathioprine--
BADD_D00214Basiliximab--
BADD_D00217Beclomethasone--
BADD_D00219Beclomethasone dipropionate--
BADD_D00220Beclomethasone dipropionate monohydrate--
BADD_D00263Betaxolol--
BADD_D00269Bexarotene0.000799%
BADD_D00271Bicalutamide0.012889%
BADD_D00274Bimatoprost0.003013%
BADD_D00284Bortezomib0.001066%
BADD_D00285Bosentan--
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