Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Carpal tunnel syndrome
ADR ID BADD_A00806
ADR Hierarchy
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.02      Mononeuropathies
17.09.02.001      Carpal tunnel syndrome
Description Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45) [MeSH]
MedDRA Code 10007697
MeSH ID D002349
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Carpal tunnel syndrome | Carpel tunnel syndrome | Syndrome carpel tunnel | Unilateral carpal tunnel syndrome | Carpal Tunnel Syndrome | Carpal Tunnel Syndromes | Syndrome, Carpal Tunnel | Syndromes, Carpal Tunnel | Amyotrophy, Thenar, Of Carpal Origin | Median Neuropathy, Carpal Tunnel | Compression Neuropathy, Carpal Tunnel | Entrapment Neuropathy, Carpal Tunnel
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.003940%
BADD_D00085Alprazolam0.000084%
BADD_D00142Anastrozole0.000492%
BADD_D00151Apixaban0.002252%
BADD_D00156Apremilast0.007527%
BADD_D00165Aripiprazole--
BADD_D00178Atenolol0.000074%
BADD_D00312Bupropion--
BADD_D00410Celecoxib0.000230%
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00564Dabigatran etexilate--
BADD_D00566Dabrafenib0.000533%
BADD_D00574Dalfampridine0.003921%
BADD_D00576Danazol--
BADD_D00680Dimethyl fumarate0.005501%
BADD_D00734Duloxetine0.000198%
BADD_D00773Entacapone--
BADD_D00782Epinephrine0.000579%
BADD_D00809Escitalopram--
BADD_D00821Estradiol--
BADD_D00852Etonogestrel0.001237%
BADD_D00861Exemestane0.007189%
BADD_D00898Finasteride0.000962%
BADD_D00947Fluticasone propionate0.000221%
BADD_D00981Gabapentin0.000102%
BADD_D01022Gliclazide--
BADD_D01067Hex-hgrf--
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01162Insulin detemir--
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