Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dalfampridine
Drug ID BADD_D00574
Description Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Indications and Usage Dalfampridine is a neurofunctional modifier that helps improve walking speed in patients with multiple sclerosis (MS).
Marketing Status Prescription
ATC Code N07XX07
DrugBank ID DB06637
KEGG ID D04127
MeSH ID D015761
PubChem ID 1727
TTD Drug ID D08YIN
NDC Product Code 38779-3205; 42571-338; 63190-0510; 46016-5042; 16729-292; 56125-427; 62756-429; 0054-0479; 42571-275; 51927-5030; 12817-054; 54382-125; 62756-038; 63190-0530; 51407-246; 65862-917; 65372-1157; 65862-863; 62991-3143; 67877-444; 10144-427; 0378-0509
Synonyms 4-Aminopyridine | 4 Aminopyridine | Dalfampridine | Pymadine | VMI-103 | VMI 103 | VMI103 | 4-Aminopyridine Sustained Release | 4 Aminopyridine Sustained Release | Sustained Release, 4-Aminopyridine | Fampridine-SR | Fampridine SR
Chemical Information
Molecular Formula C5H6N2
CAS Registry Number 504-24-5
SMILES C1=CN=CC=C1N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Abnormal dreams19.02.03.001; 17.15.02.0010.007843%Not Available
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Adenocarcinoma16.16.01.0040.000682%Not Available
Agitation19.06.02.001; 17.02.05.012--
Alanine aminotransferase abnormal13.03.01.0010.002614%Not Available
Alanine aminotransferase increased13.03.01.0030.024836%
Albumin urine present13.13.02.0120.002614%Not Available
Alopecia23.02.02.001--
Amnesia19.20.01.001; 17.03.02.0010.018300%
Anaemia01.03.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anger19.04.02.001--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anion gap increased13.02.01.0140.002614%Not Available
Ankle fracture15.08.03.005; 12.04.01.0050.011764%
Anxiety19.06.02.002--
Aphasia19.21.01.001; 17.02.03.0010.010457%
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Aspartate aminotransferase increased13.03.01.0060.014379%
Asthenia08.01.01.0010.145095%Not Available
Ataxia17.02.02.001; 08.01.02.0040.005229%
Atelectasis22.01.02.0010.002614%
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