Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypersensitivity
ADR ID BADD_A02145
ADR Hierarchy
10      Immune system disorders
10.01      Allergic conditions
10.01.03      Allergic conditions NEC
10.01.03.003      Hypersensitivity
Description Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. [MeSH]
MedDRA Code 10020751
MeSH ID D006967; D006967; D006967
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute allergic reaction | Allergic reaction | Allergic reaction NOS | Allergy | Allergy aggravated | Allergy NOS | Allergy, unspecified, not elsewhere classified | Hypersensitivity | Hypersensitivity NOS | Hypersensitivity reaction | Hypersensitivity reaction (NOS) | Hypersensitivity symptom | HYSN | Reaction allergic (NOS) | Reaction hypersensitivity (NOS) | Red neck syndrome | Upper respiratory tract hypersensitivity reaction, site unspecified | Allergic reaction (NOS) | Environmental allergy | Systemic allergic reaction | Hypersensitivities | Allergies | Allergic Reaction | Allergic Reactions | Reaction, Allergic | Reactions, Allergic
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
ATP-dependent bile acid permeaseP32386Not Available
ATP-dependent translocase ABCB1P08183T25258
Epoxide hydrolase 1P07099Not Available
HLA class I histocompatibility antigen, B alpha chainP01889Not Available
Lanosterol 14-alpha demethylaseQ8K0C4Not Available
N-alpha-acetyltransferase 20P61599Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000011,2-hexanediol--
BADD_D000054-oxo-3-(3-oxo-1-phenylbutyl)chromen-2-olate--
BADD_D000064r,6r-dorzolamide--
BADD_D000075-tert-butyl-2-methyl-1,3-benzodioxole--
BADD_D00008Abacavir0.066114%
BADD_D00010Abacavir sulfate--
BADD_D00011Abarelix--
BADD_D00013Abciximab--
BADD_D00014Abiraterone--
BADD_D00016Acamprosate--
BADD_D00017Acamprosate calcium--
BADD_D00018Acarbose--
BADD_D00022Acenocoumarol--
BADD_D00023Acetaminophen0.000268%
BADD_D00029Acetyl sulfisoxazole--
BADD_D00032Acetylcysteine0.001616%
BADD_D00033Acetylsalicylic acid--
BADD_D00034Acid citrate dextrose--
BADD_D00036Acitretin--
BADD_D00039Acyclovir0.000313%
BADD_D00041Adalimumab--
BADD_D00042Adapalene--
BADD_D00045Adenosine--
BADD_D00048Aflibercept--
BADD_D00049Agalsidase beta--
BADD_D00051Airduo respiclick--
BADD_D00052Albendazole--
BADD_D00054Albumin (human)--
BADD_D00055Albumin microspheres (human)--
BADD_D00056Albuterol--
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