| Drug Name |
Albumin (human) |
| Drug ID |
BADD_D00054 |
| Description |
Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood [A33706]. It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately 50% of the total protein content in healthy humans [A40060].
Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III). Each domain comprises two separate sub-domains (A and B) [A40060].
There are various preparations of albumin that are well established and widely available in the clinical setting [L3108], [L3109], [L3101].
Also known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229]. This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. |
| Indications and Usage |
For treatment of severe blood loss, hypervolemia, and hypoproteinemia. |
| Marketing Status |
Not Available |
| ATC Code |
B05AA01 |
| DrugBank ID |
DB00062
|
| KEGG ID |
D02792
|
| MeSH ID |
D000075462
|
| PubChem ID |
Not Available
|
| TTD Drug ID |
D0I0VI
|
| NDC Product Code |
68516-5214; 68516-5216; 13533-692; 13533-691; 76125-790; 68516-5215; 76125-791; 76179-025; 61953-0002; 13533-690; 0053-7680; 44206-310; 44206-251; 76125-792; 61953-0001 |
| Synonyms |
Serum Albumin, Human | Albumin, Human Serum | Human Serum Albumin | Albumin Human | Human, Albumin | Human Albumin | Albumin, Human |
