Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alcaftadine
Drug ID BADD_D00058
Description Alcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.
Indications and Usage For the prevention of itching associated with allergic conjunctivitis.
Marketing Status Prescription
ATC Code S01GX11
DrugBank ID DB06766
KEGG ID D06552
MeSH ID C557708
PubChem ID 19371515
TTD Drug ID D0O7JW
NDC Product Code 12502-5263; 0023-4291; 14501-0020; 0023-4290; 42973-204
Synonyms alcaftadine
Chemical Information
Molecular Formula C19H21N3O
CAS Registry Number 147084-10-4
SMILES CN1CCC(=C2C3=CC=CC=C3CCN4C2=NC=C4C=O)CC1
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation08.01.09.029; 17.02.06.001--Not Available
Conjunctival oedema06.04.01.0010.009714%Not Available
Conjunctivitis11.01.06.012; 06.04.01.0020.048572%
Corneal oedema06.04.02.0010.009714%Not Available
Dermatitis allergic23.03.04.003; 10.01.03.014--Not Available
Drug hypersensitivity10.01.01.0010.029143%Not Available
Erythema23.03.06.0010.009714%Not Available
Erythema of eyelid23.03.06.006; 06.04.04.0030.048572%Not Available
Eye allergy06.04.05.010; 10.01.03.0280.009714%Not Available
Eye discharge06.04.05.0010.034000%Not Available
Eye disorder06.08.03.0010.014571%Not Available
Eye infection11.01.06.001; 06.04.05.0070.009714%
Eye inflammation06.04.05.0020.024286%Not Available
Eye irritation06.04.05.0030.189429%Not Available
Eye pain06.08.03.0020.087429%
Eye swelling06.08.03.0030.082572%Not Available
Eyelid oedema23.04.01.003; 10.01.05.001; 06.04.04.0040.053429%Not Available
Eyelid ptosis17.17.02.004; 06.05.01.0020.009714%Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.0140.014571%Not Available
Headache17.14.01.0010.019429%
Hyperaemia24.03.02.0020.009714%Not Available
Hypersensitivity10.01.03.0030.048572%
Influenza22.07.02.001; 11.05.03.001--Not Available
Influenza like illness08.01.03.0100.014571%
Instillation site pain12.07.01.008; 08.02.01.008--Not Available
Keratitis06.04.02.0020.009714%
Lacrimation increased06.08.02.0040.029143%
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
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