Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hepatic function abnormal
ADR ID BADD_A02005
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.02      Hepatic enzymes and function abnormalities
09.01.02.001      Hepatic function abnormal
Description Not Available
MedDRA Code 10019670
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute derangement of liver function | Dysfunction hepatic nonicteric | Function liver abnormal | Function liver decreased | Hepatic dysfunction allergic | Hepatic dysfunction nonicteric | Hepatic dysfunction NOS | Hepatic dysfunction transient | Hepatic function abnormal | Hepatic function abnormal NOS | Hepatic function aggravated | Hepatic function decreased | Hepatic function disorder | Impaired liver function | Hepatic function abnormal aggr. | Hepatic dysfunction non-icteric | Dysfunction hepatic non-icteric
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Albumin-8P23110Not Available
Cyclin-A1Q61456Not Available
Cyclin-FP51944Not Available
Epidermal growth factor receptorP00533T59328
G1/S-specific cyclin-D1P25322Not Available
G2/mitotic-specific cyclin-B1P24860Not Available
G2/mitotic-specific cyclin-B2P30276Not Available
Glycogen [starch] synthase, muscleP13807Not Available
HaptoglobinP00738T17710
Hepatocyte growth factorP14210T83797
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000054-oxo-3-(3-oxo-1-phenylbutyl)chromen-2-olate--
BADD_D00014Abiraterone--
BADD_D00018Acarbose--
BADD_D00023Acetaminophen--
BADD_D00025Acetazolamide--
BADD_D00036Acitretin--
BADD_D00039Acyclovir--
BADD_D00044Adefovir dipivoxil--
BADD_D00047Afatinib--
BADD_D00073Aliskiren--
BADD_D00074Aliskiren hemifumarate--
BADD_D00076Allopurinol--
BADD_D00079Alogliptin--
BADD_D00085Alprazolam--
BADD_D00100Ambrisentan--
BADD_D00103Amikacin--
BADD_D00105Amiloride hydrochloride--
BADD_D00115Amiodarone--
BADD_D00116Amiodarone hydrochloride--
BADD_D00119Amitriptyline hydrochloride--
BADD_D00121Amlodipine--
BADD_D00128Amoxapine--
BADD_D00129Amoxicillin--
BADD_D00132Amphotericin b--
BADD_D00142Anastrozole--
BADD_D00151Apixaban--
BADD_D00156Apremilast--
BADD_D00165Aripiprazole--
BADD_D00175Asparaginase--
BADD_D00176Atazanavir--
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