Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Glaucoma
ADR ID BADD_A01837
ADR Hierarchy
06      Eye disorders
06.03      Glaucoma and ocular hypertension
06.03.01      Glaucomas (excl congenital)
06.03.01.002      Glaucoma
Description A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. [CTCAE] An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) [MeSH]
MedDRA Code 10018304
MeSH ID D005901; D005901; D015355
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Corticosteroid-induced glaucoma | Corticosteroid-induced glaucoma, glaucomatous stage | Corticosteroid-induced glaucoma, residual stage | Glaucoma | Glaucoma (excl congenital) | Glaucoma associated with anomalies of iris | Glaucoma associated with congenital anomalies, dystrophies, and systemic syndromes | Glaucoma associated with disorders of the lens | Glaucoma associated with ocular inflammations | Glaucoma associated with other anterior segment anomalies | Glaucoma associated with other lens disorders | Glaucoma associated with other ocular disorders | Glaucoma associated with systemic syndromes | Glaucoma associated with tumors or cysts | Glaucoma associated with unspecified ocular disorder | Glaucoma associated with vascular disorders | Glaucoma both eyes | Glaucoma NOS | Glaucoma of childhood | Glaucoma secondary | Glaucoma steroid-induced | Glaucoma with increased episcleral venous pressure | Glaucoma, unspecified | Other specified forms of glaucoma | Other specified glaucoma | Secondary glaucoma | Unspecified glaucoma | Glaucoma aggravated | Neovascular glaucoma | Lens induced glaucoma | Lens particle glaucoma | Absolute glaucoma | Glaucomas
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00051Airduo respiclick--
BADD_D00066Alendronic acid0.003940%
BADD_D00085Alprazolam0.000167%
BADD_D00100Ambrisentan--
BADD_D00115Amiodarone0.000893%
BADD_D00142Anastrozole0.001508%
BADD_D00151Apixaban--
BADD_D00156Apremilast--
BADD_D00159Arformoterol--
BADD_D00160Arformoterol tartrate--
BADD_D00165Aripiprazole0.001335%
BADD_D00182Atorvastatin calcium--
BADD_D00195Azathioprine0.001436%
BADD_D00217Beclomethasone--
BADD_D00219Beclomethasone dipropionate--
BADD_D00220Beclomethasone dipropionate monohydrate--
BADD_D00260Betamethasone0.000594%
BADD_D00274Bimatoprost0.001722%
BADD_D00284Bortezomib0.000533%
BADD_D00285Bosentan--
BADD_D00294Brimonidine0.001798%
BADD_D00296Brinzolamide0.006431%
BADD_D00306Budesonide--
BADD_D00326Butylscopolamine bromide--
BADD_D00335Calcitonin--
BADD_D00356Carbamazepine0.001684%
BADD_D00407Cefuroxime0.000639%
BADD_D00410Celecoxib0.000230%
BADD_D00417Cetirizine0.000035%
BADD_D00418Cetirizine hydrochloride--
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