Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Arformoterol
Drug ID BADD_D00159
Description Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. Arformoterol inhalation is used to prevent bronchoconstriction in people with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients using long acting beta agonists for the treatment of asthma.
Indications and Usage A bronchodilator used for the long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Marketing Status approved; investigational
ATC Code R03CC15; R03AC13
DrugBank ID DB01274
KEGG ID D07463
MeSH ID D000068759
PubChem ID 3083544
TTD Drug ID D0D1DI
NDC Product Code Not Available
UNII F91H02EBWT
Synonyms Formoterol Fumarate | Formoterol Fumarate, ((R*,R*)-(+-))-isomer | 3-Formylamino-4-hydroxy-alpha-(N-1-methyl-2-p-methoxyphenethylaminomethyl)benzyl alcohol.hemifumarate | BD 40A | Formoterol | Eformoterol | Oxis | Arformoterol | Formoterol, ((R*,R*)-(+-))-isomer | Foradil
Chemical Information
Molecular Formula C19H24N2O4
CAS Registry Number 67346-49-0
SMILES CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abscess11.01.08.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Angina pectoris24.04.04.002; 02.02.02.002--
Arrhythmia02.03.02.001--Not Available
Arteriosclerosis24.04.02.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Atrial flutter02.03.03.003--
Atrioventricular block02.03.01.002--Not Available
Back pain15.03.04.005--
Bladder pain20.02.02.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Breast neoplasm21.05.01.004; 16.10.02.001--Not Available
Bronchitis11.01.09.001; 22.07.01.001--
Cardiac failure congestive02.05.01.002--Not Available
Cerebral infarction24.04.06.002; 17.08.01.004--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chronic obstructive pulmonary disease22.03.01.007--Not Available
Constipation07.02.02.001--
Cystitis20.03.02.002; 11.01.14.001--
Dehydration14.05.05.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspnoea02.11.05.003; 22.02.01.004--
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