| ADR Ontology |
| ADR Term |
Generalised tonic-clonic seizure |
| ADR ID |
BADD_A01810 |
| ADR Hierarchy |
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| Description |
Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14) [MeSH] |
| MedDRA Code |
10018100 |
| MeSH ID |
D004829; D004830; D012640
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Clonic-tonic convulsions | Convulsion grand mal | Convulsions grand mal | Epilepsy grand mal | Generalised tonic-clonic seizure | Generalized convulsive epilepsy | Generalized convulsive epilepsy, with intractable epilepsy | Generalized convulsive epilepsy, without mention of intractable epilepsy | Grand mal | Grand mal convulsion | Grand mal epilepsy | Grand mal epileptic fit | Grand mal fit | Grand mal seizure | Major convulsion | Seizure grand mal | Tonic-clonic convulsion | Tonic-clonic epilepsy | Tonic-clonic seizures | Tonic/ clonic convulsions | Generalized tonic-clonic seizure | Generalised convulsive epilepsy | Epilepsy, Generalized | Epilepsies, Generalized | Generalized Epilepsies | Generalized Epilepsy | Seizure Disorder, Generalized | Generalized Seizure Disorder | Generalized Seizure Disorders | Seizure Disorders, Generalized | Epilepsy, Akinetic | Akinetic Epilepsies | Akinetic Epilepsy | Epilepsies, Akinetic | Symptomatic Generalized Epilepsy | Epilepsy, Symptomatic Generalized | Generalized Epilepsy, Symptomatic | Epilepsy, Tonic | Epilepsies, Tonic | Tonic Epilepsies | Tonic Epilepsy | Generalized Nonconvulsive Seizure Disorder | Generalized Seizure Disorder, Nonconvulsive | Seizure Disorder, Nonconvulsive Generalized | Nonconvulsive Seizure Disorder, Generalized | Seizure Disorder, Generalized Nonconvulsive | Generalized Nonconvulsive Epilepsy | Epilepsy, Generalized Nonconvulsive | Nonconvulsive Epilepsy, Generalized | Nonconvulsive Generalized Seizure Disorder | Convulsive Generalized Seizure Disorder | Generalized Convulsive Epilepsy | Convulsive Epilepsies, Generalized | Convulsive Epilepsy, Generalized | Epilepsies, Generalized Convulsive | Epilepsy, Generalized Convulsive | Generalized Convulsive Epilepsies | Generalized Onset Seizure Disorder | Seizure Disorder, Convulsive, Generalized | Seizure Disorder, Generalized Onset | Seizure Disorder, Generalized, Convulsive | Convulsive Seizure Disorder, Generalized | Generalized Seizure Disorder, Convulsive | Epilepsy, Atonic | Atonic Epilepsies | Atonic Epilepsy | Epilepsies, Atonic |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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