Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Intellectual disability
ADR ID BADD_A06480
ADR Hierarchy
17      Nervous system disorders
17.03      Mental impairment disorders
17.03.07      Intellectual disabilities
17.03.07.001      Intellectual disability
19      Psychiatric disorders
19.21      Cognitive and attention disorders and disturbances
19.21.06      Intellectual disabilities
19.21.06.001      Intellectual disability
Description Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28) [MeSH]
MedDRA Code 10067989
MeSH ID D008607; D008607; D008607
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Deficiency mental | Educationally subnormal | Feeble-minded | Idiocy | Idiot | Imbecile | Imbecility | Mental deficiency | Mental handicap NOS | Mental retardation | Mental retardation severity unspecified | Mild mental retardation | Moderate mental retardation | Moronity | Oligophrenia | Other specified mental retardation | Profound mental retardation | Retardation mental | Unspecified mental retardation | Intellectual disability | Intellectual development disorder | Intellectual Disability | Disabilities, Intellectual | Intellectual Disabilities | Retardation, Mental | Intellectual Development Disorder | Development Disorder, Intellectual | Development Disorders, Intellectual | Disorder, Intellectual Development | Disorders, Intellectual Development | Intellectual Development Disorders | Mental Retardation | Disability, Intellectual | Mental Retardation, Psychosocial | Mental Retardations, Psychosocial | Psychosocial Mental Retardation | Psychosocial Mental Retardations | Retardation, Psychosocial Mental | Retardations, Psychosocial Mental | Deficiency, Mental | Deficiencies, Mental | Mental Deficiencies | Mental Deficiency
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin0.005728%
BADD_D00085Alprazolam--
BADD_D00165Aripiprazole--
BADD_D00283Boceprevir--
BADD_D00349Capecitabine--
BADD_D00356Carbamazepine0.002105%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00511Clozapine0.030826%
BADD_D00599Degarelix--
BADD_D00648Diazepam0.000320%
BADD_D00794Ergocalciferol--
BADD_D00870Febuxostat--
BADD_D00932Fluoxetine0.000272%
BADD_D00952Folic acid0.000706%
BADD_D01243Lamotrigine0.000516%
BADD_D01265Levetiracetam0.002666%
BADD_D01285Levothyroxine0.000034%
BADD_D01477Misoprostol0.002826%
BADD_D01479Mitotane--
BADD_D01527Naltrexone--
BADD_D01549Nelarabine--
BADD_D01572Nitisinone0.096124%
BADD_D01617Ondansetron0.000150%
BADD_D01637Oxcarbazepine0.000831%
BADD_D01648Oxymorphone--
BADD_D01679Paroxetine0.000935%
BADD_D01835Pregabalin--
BADD_D01854Promethazine0.002785%
BADD_D01888Quetiapine0.000764%
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