Drug Name |
Nitisinone |
Drug ID |
BADD_D01572 |
Description |
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin. |
Indications and Usage |
Used as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1. |
Marketing Status |
Prescription |
ATC Code |
A16AX04 |
DrugBank ID |
DB00348
|
KEGG ID |
D05177
|
MeSH ID |
C077073
|
PubChem ID |
115355
|
TTD Drug ID |
D0V1UW
|
NDC Product Code |
63629-2235; 55463-0034; 0254-3020; 43235-0016; 70709-000; 66658-110; 70709-005; 63629-2233; 63069-075; 24196-194; 63069-072; 0254-3022; 63069-071; 66658-105; 66658-120; 76438-004; 0254-3021; 76055-0043; 68022-7058; 66658-204; 66658-102; 70709-002; 58159-037; 63629-2234 |
Synonyms |
nitisinone | NTBC cpd | 2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione | 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione | Orfadin |