Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Clomiphene citrate
Drug ID BADD_D00498
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status approved; investigational
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D00962
MeSH ID D002996
PubChem ID 60974
TTD Drug ID D0I5WB
NDC Product Code 51927-0249; 73377-229; 49884-701; 50090-0678; 10577-916; 46014-1122; 51927-0056; 0713-0885; 73212-029; 63629-2165; 63629-5302; 63275-9964; 63629-9276; 48087-0025; 49169-1040; 51552-1580; 68071-2638; 73309-047; 50090-6500; 17369-817; 48087-0144; 62991-2702; 61919-375; 38779-0390; 43647-456; 71052-338; 90027-025
UNII 1B8447E7YI
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C32H36ClNO8
CAS Registry Number 50-41-9
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O) O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Accommodation disorder06.02.04.001--Not Available
Acne23.02.01.001--Not Available
Acute abdomen07.01.06.015--Not Available
Alopecia23.02.02.001--
Amniocentesis13.21.01.002--Not Available
Anal atresia07.13.05.001; 03.04.06.001--Not Available
Anencephaly17.19.03.001; 03.10.03.001--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Astrocytoma17.20.01.002; 16.30.01.002--Not Available
Atrial septal defect03.07.02.002; 02.04.02.009--Not Available
Back pain15.03.04.005--
Benign hydatidiform mole16.04.01.002; 21.07.02.006; 18.05.03.001--Not Available
Bladder cancer20.03.04.001; 16.08.01.001--Not Available
Blindness06.02.10.003; 17.17.01.003--Not Available
Brain abscess17.06.07.001; 11.01.03.003--Not Available
Breast cancer16.10.01.001; 21.05.01.003--Not Available
Cataract06.06.01.001--
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Choriocarcinoma16.16.04.001--Not Available
Cleft lip and palate07.05.08.003; 03.04.02.003--Not Available
Coarctation of the aorta24.04.01.002; 03.07.08.001--Not Available
Constipation07.02.02.001--
Deafness04.02.01.001--Not Available
Depression19.15.01.001--
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