Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clomiphene
Drug ID BADD_D00497
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status approved; investigational
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D07726
MeSH ID D002996
PubChem ID 1548953
TTD Drug ID D0CT9Y
NDC Product Code Not Available
UNII 1HRS458QU2
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C26H28ClNO
CAS Registry Number 15690-57-0
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Accommodation disorder06.02.04.001--Not Available
Acne23.02.01.001--Not Available
Acute abdomen07.01.06.015--Not Available
Alopecia23.02.02.001--
Amaurosis06.02.10.001--Not Available
Anal atresia07.13.05.001; 03.04.06.001--Not Available
Anencephaly03.10.03.001; 17.19.03.001--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arteriovenous fistula24.03.03.001--Not Available
Arthralgia15.01.02.001--
Ascites07.07.01.001; 02.05.04.002; 09.01.05.003--
Asthenia08.01.01.001--Not Available
Astrocytoma17.20.01.002; 16.30.01.002--Not Available
Back pain15.03.04.005--
Bladder cancer20.03.04.001; 16.08.01.001--Not Available
Blindness17.17.01.003; 06.02.10.003--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bone development abnormal15.02.04.003--Not Available
Brain abscess17.06.07.001; 11.01.03.003--Not Available
Breast cancer21.05.01.003; 16.10.01.001--Not Available
Breast tenderness21.05.05.004--Not Available
Cataract06.06.01.001--
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain02.02.02.011; 22.12.02.003; 08.01.08.002--Not Available
Cholestasis09.01.01.001--Not Available
Choriocarcinoma16.16.04.001--Not Available
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