Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bone marrow failure
ADR ID BADD_A06316
ADR Hierarchy
01      Blood and lymphatic system disorders
01.03      Anaemias nonhaemolytic and marrow depression
01.03.03      Marrow depression and hypoplastic anaemias
01.03.03.005      Bone marrow failure
Description Not Available
MedDRA Code 10065553
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Aplasia bone marrow | Aplastic marrow | Bone marrow aplastic | Bone marrow depression | Bone marrow depression NOS | Depression bone marrow (NOS) | Haematopoiesis decreased | Haematopoiesis impaired | Haematopoiesis suppressed | Haemopoiesis decreased | Haemopoiesis impaired | Haemopoiesis suppressed | Hematopoiesis depressed | Hematopoiesis impaired | Hematopoiesis suppressed | Hypocellular marrow | Hypoplasia bone marrow | Hypoplasia erythroid | Hypoplastic marrow | Marrow depression | Marrow depression of | Marrow hypoplasia | Myelosuppression | Myelosuppression adult | Bone marrow hypocellular | Haematopoiesis depressed | Hematopoiesis decreased | Hemopoiesis decreased | Hemopoiesis impaired | Hemopoiesis suppressed | Bone marrow failure
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
ATP-binding cassette sub-family C member 8Q09428T91480
ATP-dependent translocase ABCB1P08183T25258
Beta-2 adrenergic receptorP07550T52522
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
ErythropoietinP01588T07958
Granulocyte colony-stimulating factor receptorQ99062T98913
Granulocyte-macrophage colony-stimulating factorP04141T74002
Interleukin-3P08700Not Available
Thiopurine S-methyltransferaseP51580Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone--
BADD_D00044Adefovir dipivoxil--
BADD_D00047Afatinib--
BADD_D00052Albendazole--
BADD_D00076Allopurinol--
BADD_D00079Alogliptin--
BADD_D00085Alprazolam--
BADD_D00088Altretamine--
BADD_D00115Amiodarone--
BADD_D00116Amiodarone hydrochloride--
BADD_D00118Amitriptyline--
BADD_D00119Amitriptyline hydrochloride--
BADD_D00121Amlodipine--
BADD_D00129Amoxicillin--
BADD_D00132Amphotericin b--
BADD_D00137Amsacrine--
BADD_D00151Apixaban--
BADD_D00178Atenolol--
BADD_D00193Axitinib--
BADD_D00194Azacitidine--
BADD_D00195Azathioprine--
BADD_D00196Azathioprine sodium--
BADD_D00230Bendamustine--
BADD_D00231Bendamustine hydrochloride--
BADD_D00269Bexarotene--
BADD_D00271Bicalutamide--
BADD_D00280Bleomycin--
BADD_D00284Bortezomib--
BADD_D00286Bosutinib--
BADD_D00287Bosutinib monohydrate--
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