Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Carbimazole
Drug ID BADD_D00360
Description An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Indications and Usage For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
Marketing Status Not Available
ATC Code H03BB01
DrugBank ID DB00389
KEGG ID D07616
MeSH ID D002231
PubChem ID 31072
TTD Drug ID D02CKX
NDC Product Code Not Available
Synonyms Carbimazole | Carbimazole Henning | Neo-Thyreostat | Neomercazole | Neo-Mercazole | Neo Tomizol
Chemical Information
Molecular Formula C7H10N2O2S
CAS Registry Number 22232-54-8
SMILES CCOC(=O)N1C=CN(C1=S)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ageusia17.02.07.001; 07.14.03.003--Not Available
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Angioedema10.01.05.009; 23.04.01.001--Not Available
Aplastic anaemia01.03.03.002--Not Available
Arthralgia15.01.02.001--
Body temperature increased13.15.01.001--Not Available
Cutaneous vasculitis24.05.02.004; 23.06.02.001; 10.02.02.003--Not Available
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Eosinophilia01.02.04.001--
Feeling abnormal08.01.09.014--Not Available
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hepatitis cholestatic09.01.01.002--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hypersensitivity10.01.03.003--
Hypogeusia17.02.07.004; 07.14.03.002--Not Available
Infection11.01.08.002--Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Liver disorder09.01.08.001--Not Available
Liver function test abnormal13.03.01.013--Not Available
Malaise08.01.01.003--
Mouth ulceration07.05.06.004--Not Available
Myalgia15.05.02.001--
Myopathy15.05.05.001--Not Available
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