| Drug Name |
Azathioprine sodium |
| Drug ID |
BADD_D00196 |
| Description |
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.[L11214]
Azathiprine was granted FDA approval on 20 March 1968.[L11214] |
| Indications and Usage |
Anstey A, Lear JT: Azathioprine: clinical pharmacology and current indications in autoimmune disorders. BioDrugs. 1998 Jan;9(1):33-47. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
L04AX01 |
| DrugBank ID |
DB00993
|
| KEGG ID |
D03033
|
| MeSH ID |
D001379
|
| PubChem ID |
11529527
|
| TTD Drug ID |
D07QCE
|
| NDC Product Code |
0143-9566 |
| Synonyms |
Azathioprine | Azothioprine | Imurel | Imuran | Immuran | Azathioprine Sodium | Sodium, Azathioprine | Azathioprine Sodium Salt | Azathioprine Sulfate |
