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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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ADR Ontology
ADR Term
Inflammation
ADR ID
BADD_A05823
ADR Hierarchy
08
General disorders and administration site conditions
08.01
General system disorders NEC
08.01.05
Inflammations
08.01.05.007
Inflammation
Description
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code
10061218
MeSH ID
D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Interleukin-1 alpha
P01583
T16340
Interleukin-10
P29456
Not Available
Interleukin-6
P05231
T32578
Interleukin-8
P10145
T22658
Nuclear receptor subfamily 4 group A member 3
Q92570
T93949
Retinol-binding protein 1
P09455
Not Available
Tumor necrosis factor
P01375
T20178
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00008
Abacavir
-
-
BADD_D00013
Abciximab
-
-
BADD_D00032
Acetylcysteine
0.001292%
BADD_D00039
Acyclovir
-
-
BADD_D00040
Acyclovir sodium
-
-
BADD_D00047
Afatinib
0.002131%
BADD_D00056
Albuterol
-
-
BADD_D00062
Aldesleukin
-
-
BADD_D00066
Alendronic acid
0.001414%
BADD_D00075
Alitretinoin
-
-
BADD_D00076
Allopurinol
-
-
BADD_D00085
Alprazolam
-
-
BADD_D00100
Ambrisentan
-
-
BADD_D00115
Amiodarone
0.001488%
BADD_D00129
Amoxicillin
-
-
BADD_D00132
Amphotericin b
-
-
BADD_D00136
Amprenavir
-
-
BADD_D00137
Amsacrine
-
-
BADD_D00142
Anastrozole
-
-
BADD_D00151
Apixaban
-
-
BADD_D00152
Apomorphine
0.000849%
BADD_D00154
Apraclonidine
-
-
BADD_D00156
Apremilast
0.031845%
BADD_D00165
Aripiprazole
-
-
BADD_D00172
Asenapine
-
-
BADD_D00173
Asenapine maleate
-
-
BADD_D00176
Atazanavir
-
-
BADD_D00178
Atenolol
0.000111%
BADD_D00193
Axitinib
0.001066%
BADD_D00194
Azacitidine
0.001865%
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