Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acyclovir sodium
Drug ID BADD_D00040
Description Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis[L7303,L7315,L7318,L7321,L7324,L7327]. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.[L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318]
Indications and Usage For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox.
Marketing Status Prescription; Discontinued
ATC Code D06BB03; J05AB01; S01AD03
DrugBank ID DB00787
KEGG ID D02764
MeSH ID D000212
PubChem ID 23665721
TTD Drug ID D0B5MP
NDC Product Code 63323-325; 55150-155; 46014-1019; 55150-154; 14335-150
Synonyms Acyclovir | 9-((2-Hydroxyethoxy)methyl)guanine | Aciclovir | Acycloguanosine | Herpoviric | Aciclobeta | Aciclostad | Isavir | Laciken | Mapox | Maynar | Milavir | Opthavir | Supraviran | Viclovir | Vipral | Virax-Puren | Virax Puren | ViraxPuren | Virherpes | Virmen | Virolex | Virupos | Virzin | Wellcome-248U | Wellcome 248U | Wellcome248U | Zoliparin | Zovirax | Zyclir | Aciclovir Alonga | Alonga, Aciclovir | Acifur | Acipen Solutab | Solutab, Acipen | Acivir | Activir | Acyclo-V | Acyclo V | Acyclovir Sodium | Sodium, Acyclovir | Antiherpes Creme | aciclovir von ct | Avirax | Cicloferon | Clonorax | Cusiviral | Genvir | Herpetad | Herpofug | Herpotern | Aci-Sanorania | Aci Sanorania | Aciclovir-Sanorania | Aciclovir Sanorania | Acic
Chemical Information
Molecular Formula C8H10N5NaO3
CAS Registry Number 69657-51-8
SMILES C1=NC2=C(N1COCCO)N=C(N=C2[O-])N.[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Neurological symptomMyelin basic proteinP02686T54761Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Aggression19.05.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Blood creatinine increased13.13.01.004--
Blood urea13.13.01.019--Not Available
Blood urea increased13.13.01.006--Not Available
Coma17.02.09.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Delirium19.13.02.001--
Depressed level of consciousness17.02.04.002--
Diarrhoea07.02.01.001--
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dysaesthesia17.02.06.003--
Encephalopathy17.13.02.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Haematuria24.07.01.047; 20.02.01.006--
Haemolysis01.06.04.002--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hyperbilirubinaemia01.06.04.003; 14.11.01.010; 09.01.01.003--Not Available
Hypersensitivity vasculitis24.05.02.012; 23.06.02.005; 10.02.02.017; 01.01.04.008--Not Available
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