Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hydrocephalus
ADR ID BADD_A02099
ADR Hierarchy
17      Nervous system disorders
17.07      Increased intracranial pressure and hydrocephalus
17.07.01      Hydrocephalic conditions
17.07.01.001      Hydrocephalus
Description A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. [CTCAE] Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA. | Enlargement of CEREBRAL VENTRICLES. Although it is often isolated without other CNS anomalies it can be associated with other congenital malformations (e.g., ARNOLD-CHIARI MALFORMATION; DANDY-WALKER MALFORMATION, and ACROCALLOSAL SYNDROME). [MeSH]
MedDRA Code 10020508
MeSH ID D006849; D006849; D006849
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Communicating hydrocephalus | Hydrocephalus | Hydrocephalus acquired | Hydrocephalus NOS | Hydrocephaly | Hydrocephaly communicative | Hydrocephaly obstructive | Obstructive hydrocephalus | Non-communicating hydrocephalus | Post inflammatory hydrocephalus | Cerebral Ventriculomegaly | Cerebral Ventriculomegalies | Ventriculomegalies, Cerebral | Ventriculomegaly, Cerebral | Communicating Hydrocephalus | Hydrocephalus, Communicating | Congenital Hydrocephalus | Hydrocephalus, Congenital | Hydrocephalus Ex-Vacuo | Hydrocephalus Ex Vacuo | Hydrocephalus Ex-Vacuos | Obstructive Hydrocephalus | Hydrocephalus, Obstructive | Post-Traumatic Hydrocephalus | Hydrocephalus, Post-Traumatic | Post Traumatic Hydrocephalus | Aqueductal Stenosis | Aqueductal Stenoses | Stenoses, Aqueductal | Stenosis, Aqueductal | Fetal Cerebral Ventriculomegaly | Cerebral Ventriculomegalies, Fetal | Cerebral Ventriculomegaly, Fetal | Fetal Cerebral Ventriculomegalies | Ventriculomegalies, Fetal Cerebral | Ventriculomegaly, Fetal Cerebral
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000202%
BADD_D00144Antagon--
BADD_D00151Apixaban0.003444%
BADD_D00285Bosentan--
BADD_D00356Carbamazepine0.000842%
BADD_D00364Carboplatin0.001865%
BADD_D00371Carmustine0.000799%
BADD_D00475Citalopram0.000208%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00504Clopidogrel0.000077%
BADD_D00511Clozapine--
BADD_D00551Cyclosporine0.000779%
BADD_D00561Cytarabine hydrochloride--
BADD_D00564Dabigatran etexilate0.004747%
BADD_D00589Dasatinib0.000799%
BADD_D00623Dexamethasone0.000687%
BADD_D00680Dimethyl fumarate--
BADD_D00692Dipyridamole0.004474%
BADD_D00765Empagliflozin0.000749%
BADD_D00809Escitalopram0.000237%
BADD_D00858Everolimus--
BADD_D00932Fluoxetine0.000499%
BADD_D00952Folic acid0.000941%
BADD_D01005Ganirelix acetate--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01060Heparin0.011132%
BADD_D01119Ibrutinib0.000799%
BADD_D01213Isotretinoin0.001263%
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