Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Epilepsy
ADR ID BADD_A01522
ADR Hierarchy
17      Nervous system disorders
17.12      Seizures (incl subtypes)
17.12.03      Seizures and seizure disorders NEC
17.12.03.002      Epilepsy
Description A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) [MeSH]
MedDRA Code 10015037
MeSH ID D004827; D012640; D000069279
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Epilepsy | Epilepsy aggravated | Epilepsy equivalent | Epilepsy NOS | Epilepsy, unspecified | Epilepsy, unspecified, with intractable epilepsy | Epilepsy, unspecified, without mention of intractable epilepsy | Epileptic equivalent | Epileptic fit | Epileptic seizure | Epileptiform attacks (NOS) | Epileptiform attacks NOS | Epileptiform fits NOS | Epileptiform movement | Fit (in known epileptic) | Late onset epilepsy | Other forms of epilepsy | Other forms of epilepsy, with intractable epilepsy | Other forms of epilepsy, without mention of intractable epilepsy | Intractable epilepsy | Secondary epilepsy | Symptomatic epilepsy | Generalised epileptic seizure | Generalized epileptic seizure | Prolonged epileptic seizure | Refractory epilepsy | Structural epilepsy | Metabolic epilepsy | Epilepsies | Seizure Disorder | Seizure Disorders | Awakening Epilepsy | Epilepsy, Awakening | Epilepsy, Cryptogenic | Cryptogenic Epilepsies | Cryptogenic Epilepsy | Epilepsies, Cryptogenic | Aura | Auras
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00033Acetylsalicylic acid0.000055%
BADD_D00039Acyclovir0.000143%
BADD_D00047Afatinib0.000616%
BADD_D00076Allopurinol--
BADD_D00085Alprazolam0.000340%
BADD_D00129Amoxicillin--
BADD_D00132Amphotericin b--
BADD_D00152Apomorphine0.000182%
BADD_D00165Aripiprazole0.000753%
BADD_D00180Atomoxetine0.000464%
BADD_D00193Axitinib0.000616%
BADD_D00209Baclofen0.000348%
BADD_D00230Bendamustine0.000168%
BADD_D00277Bisoprolol0.000785%
BADD_D00284Bortezomib--
BADD_D00293Brexpiprazole0.000327%
BADD_D00297Brivaracetam0.000374%
BADD_D00304Bromocriptine--
BADD_D00305Bromocriptine mesylate--
BADD_D00312Bupropion0.000258%
BADD_D00318Busulfan0.000336%
BADD_D00329Cabergoline0.007207%
BADD_D00337Calcitriol0.000223%
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00356Carbamazepine0.016031%
BADD_D00371Carmustine0.000112%
BADD_D00386Cefepime0.000049%
BADD_D00407Cefuroxime0.000215%
BADD_D00410Celecoxib--
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