Adverse Drug Reaction Classification System

ADR Ontology
ADR Term IgA nephropathy
ADR ID BADD_A07308
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.063      IgA nephropathy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.016      IgA nephropathy
Description A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE. [MeSH]
MedDRA Code 10021263
MeSH ID D005922; D005922; D005922
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
IgA nephropathy | Berger's disease | Glomerulonephritis, IGA | Glomerulonephritides, IGA | Berger's Disease | Bergers Disease | IGA Glomerulonephritis | IGA Nephropathy | Immunoglobulin A Nephropathy | Nephropathy, Immunoglobulin A | Nephritis, IGA Type | IGA Type Nephritis | Nephropathy, IGA | Berger Disease | Iga Nephropathy 1 | Nephropathy 1, Iga
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00044Adefovir dipivoxil0.003617%
BADD_D00195Azathioprine0.002154%
BADD_D00466Cilostazol0.002063%
BADD_D00551Cyclosporine0.000519%
BADD_D01086Hydrocortisone0.000224%
BADD_D01204Isoniazid0.019111%
BADD_D01300Lisinopril0.000011%
BADD_D01533Naproxen0.000082%
BADD_D01954Rivaroxaban0.000535%
BADD_D02105Tacrolimus0.002839%
BADD_D02147Telmisartan0.004479%
BADD_D02155Tenofovir disoproxil0.013329%
BADD_D02373Warfarin0.000180%
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