Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal adhesions12.02.03.006; 07.07.03.0010.000035%Not Available
Abdominal distension07.01.04.0010.000384%
Abdominal pain07.01.05.0020.001213%
Abdominal rigidity07.01.05.0110.000035%Not Available
Abnormal faeces07.01.03.0010.000070%Not Available
Abortion18.01.01.0010.000035%Not Available
Abscess11.01.08.001--Not Available
Acidosis14.01.03.0020.000052%
Acne23.02.01.001--Not Available
Actinic keratosis23.01.06.0010.000035%Not Available
Acute abdomen07.01.06.0150.000070%Not Available
Acute febrile neutrophilic dermatosis23.03.03.033; 01.02.01.0060.000052%Not Available
Acute hepatic failure09.01.03.0010.000157%Not Available
Acute lymphocytic leukaemia01.10.01.001; 16.01.01.0010.000105%Not Available
Acute myeloid leukaemia01.10.05.001; 16.01.05.0010.000140%Not Available
Acute myocardial infarction24.04.04.001; 02.02.02.0010.000157%Not Available
Acute psychosis19.03.01.0010.000070%Not Available
Acute respiratory distress syndrome24.03.02.034; 10.02.01.067; 22.01.03.0010.000751%
Acute respiratory failure22.02.06.001; 14.01.04.0040.000280%Not Available
Addison's disease14.11.01.025; 10.04.08.008; 05.01.02.0060.000052%Not Available
Adrenal atrophy05.01.02.008; 14.11.01.0300.000052%Not Available
Adrenal insufficiency14.11.01.004; 05.01.02.0010.000926%
Adrenal suppression14.11.01.005; 05.01.02.0020.000140%Not Available
Adrenocortical insufficiency acute14.11.01.020; 05.01.02.0050.000262%Not Available
Affective disorder19.04.04.0010.000175%Not Available
Aggression19.05.01.0010.000280%Not Available
Agranulocytosis01.02.03.0010.000175%Not Available
Akinesia17.01.02.0030.000052%Not Available
Alkalosis14.01.02.0010.000035%
Alkalosis hypokalaemic14.01.02.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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