| ADR Ontology |
| ADR Term |
Coma hepatic |
| ADR ID |
BADD_A00986 |
| ADR Hierarchy |
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| Description |
A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5) [MeSH] |
| MedDRA Code |
10010075 |
| MeSH ID |
D006501
|
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
|
Not Available
|
| Synonym |
| Coma hepatic | Hepatic coma | Hepatic Encephalopathy | Encephalopathies, Hepatic | Hepatic Encephalopathies | Encephalopathy, Hepatic | Portal-Systemic Encephalopathy | Portal Systemic Encephalopathy | Encephalopathy, Portal-Systemic | Encephalopathies, Portal-Systemic | Encephalopathy, Portal Systemic | Portal-Systemic Encephalopathies | Encephalopathy, Portosystemic | Hepatocerebral Encephalopathy | Portosystemic Encephalopathy | Encephalopathies, Portosystemic | Portosystemic Encephalopathies | Encephalopathy, Hepatocerebral | Encephalopathies, Hepatocerebral | Hepatocerebral Encephalopathies | Hepatic Coma | Coma, Hepatic | Comas, Hepatic | Hepatic Comas | Hepatic Stupor | Hepatic Stupors | Stupor, Hepatic | Stupors, Hepatic | Fulminant Hepatic Failure with Cerebral Edema |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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