Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cyproterone acetate
Drug ID BADD_D00555
Description An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Indications and Usage For the palliative treatment of patients with advanced prostatic carcinoma.
Marketing Status Not Available
ATC Code G03HA01
DrugBank ID DB04839
KEGG ID D01368
MeSH ID D017373
PubChem ID 9880
TTD Drug ID Not Available
NDC Product Code 59010-000; 46439-8720; 53104-7635
Synonyms Cyproterone Acetate | Cyproterone Acetate, (17 alpha)-Isomer | Cyproterone Acetate, (1 alpha,2 alpha,9 beta,10 alpha)-Isomer | Androcur | Cyproterone Acetate, (1 alpha,2 alpha)-Isomer
Chemical Information
Molecular Formula C24H29ClO4
CAS Registry Number 427-51-0
SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)OC(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Accommodation disorder06.02.04.001--Not Available
Acne23.02.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anovulatory cycle21.01.01.011; 05.05.01.017--Not Available
Aphasia19.21.01.001; 17.02.03.001--
Ascites07.07.01.001; 02.05.04.002; 09.01.05.003--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrophy08.03.04.001--Not Available
Azoospermia21.03.03.001--
Bladder cancer16.08.01.001; 20.03.04.001--Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Blood creatinine increased13.13.01.004--
Body temperature increased13.15.01.001--Not Available
Breast enlargement21.05.04.001--Not Available
Breast pain21.05.05.003--
Breast tenderness21.05.05.004--Not Available
Cardiac failure02.05.01.001--
Cardiovascular disorder24.03.02.009; 02.01.01.001--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chills08.01.09.001; 15.05.03.016--
Coma17.02.09.001--Not Available
Coma hepatic17.02.09.002; 09.01.03.005--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Crystalluria20.02.01.003--Not Available
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