Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmethylphenidate hydrochloride
Drug ID BADD_D00631
Description Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002[A177181]. It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or the racemic mixture[A177181].
Indications and Usage Dexmethylphenidate is used as a treatment for ADHD, ideally in conjunction with psychological, educational, behavioral or other forms of treatment.
Marketing Status Prescription
ATC Code N06BA11
DrugBank ID DB06701
KEGG ID D03721
MeSH ID D064699
PubChem ID 154100
TTD Drug ID D02QCD
NDC Product Code 57664-624; 60274-730; 0115-1683; 0093-5553; 0781-2685; 60274-740; 60274-710; 53834-201; 0078-0380; 16714-563; 49884-048; 10702-108; 0078-0434; 57664-629; 0115-1709; 57664-621; 67877-655; 55466-123; 60274-715; 0093-5562; 57664-625; 57664-379; 11014-0314; 70010-007; 31722-229; 43602-329; 0093-5554; 31722-233; 43602-330; 0792-0619; 42858-410; 70010-010; 70010-008; 70010-004; 70010-009; 70010-006; 11014-0211; 57664-378; 57664-376; 0078-0609; 31722-230; 0078-0608; 16714-568; 31722-232; 49884-333; 11014-0317; 63629-2306; 60274-705; 11014-0316; 0527-8112; 0115-1710; 16714-564; 0115-1686; 42858-011; 31722-234; 63629-2307; 0115-9919; 63629-2177; 49884-049; 11014-0318; 67877-656; 27808-093; 0078-0430; 63629-2305; 49884-339; 31722-235; 0078-0381; 57664-622; 63629-2172; 0115-9920; 63629-2174; 43602-332; 49884-546; 43386-862; 60274-725; 0115-1682; 0078-0432; 0527-8111; 0781-2684; 0527-8106; 0527-8108; 43386-861; 63629-2178; 10702-107; 0527-8113; 0781-2686; 0078-0382; 0527-8107; 0093-5550; 0093-5045; 57664-626; 49884-248; 11014-0080; 0078-0431; 63629-2173; 16714-566; 0115-9921; 0115-1685; 0781-2689; 63629-2175; 11014-0315; 57664-628; 43602-331; 16714-569; 42858-225; 43602-327; 0093-5551; 43602-333; 31722-236; 11014-0212; 63629-2171; 63629-2176; 0078-0433; 70010-011; 0093-5552; 16714-567; 31722-231; 10702-106; 43602-334; 57664-623; 27808-091; 43602-328; 0527-8109; 16714-562; 55466-122; 17180-1725; 0781-2687; 11014-0213; 60274-720; 27808-092; 0781-2688; 49884-090; 0527-8110; 0078-0493; 0781-2682; 16714-565; 0115-9922; 0781-2683; 0115-1684; 70010-005; 0115-9918; 67877-657; 60274-735; 11014-0103; 49884-539; 43386-860; 0093-5046
Synonyms Dexmethylphenidate Hydrochloride | Hydrochloride, Dexmethylphenidate | Focalin XR | XR, Focalin | Dexmethylphenidate | Focalin
Chemical Information
Molecular Formula C14H20ClNO2
CAS Registry Number 19262-68-1
SMILES COC(=O)C(C1CCCCN1)C2=CC=CC=C2.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Aggression19.05.01.001--Not Available
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Cerebral arteritis24.05.01.002; 17.08.02.004--Not Available
Coma hepatic17.02.09.002; 09.01.03.005--Not Available
Depressed mood19.15.02.001--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug interaction08.06.03.001--Not Available
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Feeling jittery08.01.09.016--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001--Not Available
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