Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fluoxymesterone
Drug ID BADD_D00934
Description An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Indications and Usage In males, used as replacement therapy in conditions associated with symptoms of deficiency or absence of endogenous testosterone. In females, for palliation of androgenresponsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal.
Marketing Status Prescription; Discontinued
ATC Code G03BA01
DrugBank ID DB01185
KEGG ID D00327
MeSH ID D005474
PubChem ID 6446
TTD Drug ID D0L2LS
NDC Product Code 64181-0082; 0832-0086; 65089-0052
Synonyms Fluoxymesterone | Fluoximesteron | Halotestin | Stenox | Android-F | Android F
Chemical Information
Molecular Formula C20H29FO3
CAS Registry Number 76-43-7
SMILES CC12CCC(=O)C=C1CCC3C2(C(CC4(C3CCC4(C)O)C)O)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Alopecia23.02.02.001--
Amenorrhoea21.01.02.001; 05.05.01.002--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Anxiety19.06.02.002--
Azoospermia21.03.03.001--
Blood calcium13.11.01.041--Not Available
Blood chloride13.11.01.042--Not Available
Blood cholesterol increased13.12.01.002--
Blood gonadotrophin decreased13.10.03.001--Not Available
Blood phosphorus13.11.01.023--Not Available
Blood potassium13.11.01.032--Not Available
Clitoral engorgement21.08.02.006--Not Available
Coagulopathy01.01.02.001--Not Available
Coma hepatic17.02.09.002; 09.01.03.005--Not Available
Depression19.15.01.001--
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.004--
Enlarged clitoris05.05.01.004; 21.08.02.001--Not Available
Erection increased21.03.01.004; 19.08.04.002--Not Available
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hepatic neoplasm16.07.03.001; 09.04.03.001--Not Available
Hirsutism05.05.01.005; 23.02.04.001--
Hypersensitivity10.01.03.003--
Jaundice cholestatic09.01.01.005--Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Libido increased21.03.02.007; 19.08.03.002--
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