Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Aortic stenosis
ADR ID BADD_A00284
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.01      Aortic necrosis and vascular insufficiency
24.04.01.001      Aortic stenosis
Description A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA. [MeSH]
MedDRA Code 10002906
MeSH ID D001024
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Aortic stenosis | Aortic stricture | Aorto-iliac arterial stenosis | Abdominal aortic stenosis | Mid aortic syndrome | Aortic arch stenosis | Thoracic aortic stenosis | Aortic Valve Stenosis | Aortic Valve Stenoses | Stenoses, Aortic Valve | Stenosis, Aortic Valve | Valve Stenoses, Aortic | Valve Stenosis, Aortic | Aortic Stenosis | Stenoses, Aortic | Stenosis, Aortic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000334%
BADD_D00066Alendronic acid0.000374%
BADD_D00100Ambrisentan0.000385%
BADD_D00115Amiodarone0.000135%
BADD_D00121Amlodipine0.000010%
BADD_D00151Apixaban0.000325%
BADD_D00161Argatroban--
BADD_D00195Azathioprine0.000313%
BADD_D00230Bendamustine0.000168%
BADD_D00285Bosentan0.000421%
BADD_D00367Carfilzomib0.000168%
BADD_D00474Cisplatin0.000302%
BADD_D00504Clopidogrel0.000032%
BADD_D00563Dabigatran0.001223%
BADD_D00668Digoxin0.000211%
BADD_D00775Enzalutamide0.000334%
BADD_D00809Escitalopram0.000019%
BADD_D00932Fluoxetine0.000030%
BADD_D00979Furosemide0.000028%
BADD_D01083Hydrochlorothiazide0.000010%
BADD_D01119Ibrutinib0.000224%
BADD_D01257Letrozole--
BADD_D01285Levothyroxine--
BADD_D01311Lomitapide0.000021%
BADD_D01336Macitentan0.000241%
BADD_D01418Methotrexate--
BADD_D01442Metoclopramide0.000392%
BADD_D01567Nilotinib0.000783%
BADD_D01679Paroxetine0.000193%
BADD_D01783Pirfenidone0.000530%
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