Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Umbilical hernias
ADR ID BADD_A04415
ADR Hierarchy
07      Gastrointestinal disorders
07.16      Abdominal hernias and other abdominal wall conditions
07.16.03      Umbilical hernias
Description A HERNIA due to an imperfect closure or weakness of the umbilical ring. It appears as a skin-covered protrusion at the UMBILICUS during crying, coughing, or straining. The hernia generally consists of OMENTUM or SMALL INTESTINE. The vast majority of umbilical hernias are congenital but can be acquired due to severe abdominal distention. | A congenital defect with major fissure in the ABDOMINAL WALL at the UMBILICUS resulting in the extrusion of VISCERA through the UMBILICUS. Unlike GASTROSCHISIS, omphalocele is covered with PERITONEUM but without overlying SKIN. [MeSH]
MedDRA Code 10045459
MeSH ID D006554
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Hernia, Umbilical | Exomphalos | Umbilical Hernia | Hernias, Umbilical | Umbilical Hernias | Omphalocele | Omphaloceles
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug Name
BADD_D00066Alendronic acid
BADD_D00144Antagon
BADD_D00156Apremilast
BADD_D00277Bisoprolol
BADD_D00347Candesartan cilexetil
BADD_D00497Clomiphene
BADD_D00498Clomiphene citrate
BADD_D00511Clozapine
BADD_D00680Dimethyl fumarate
BADD_D00809Escitalopram
BADD_D00898Finasteride
BADD_D00932Fluoxetine
BADD_D01001Galsulfase
BADD_D01005Ganirelix acetate
BADD_D01136Imatinib
BADD_D01242Lamivudine
BADD_D01243Lamotrigine
BADD_D01253Lenalidomide
BADD_D01257Letrozole
BADD_D01265Levetiracetam
BADD_D01401Metformin
BADD_D01414Methimazole
BADD_D01567Nilotinib
BADD_D01617Ondansetron
BADD_D01627Oseltamivir
BADD_D01679Paroxetine
BADD_D01817Pramipexole
BADD_D01818Pramipexole dihydrochloride
BADD_D01835Pregabalin
BADD_D01869Propylthiouracil
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