Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisone
Drug ID BADD_D01834
Description A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Indications and Usage Diez JJ, Iglesias P: Pharmacological therapy of Cushing's syndrome: drugs and indications. Mini Rev Med Chem. 2007 May;7(5):467-80.
Marketing Status Prescription; Discontinued
ATC Code A07EA03; H02AB07
DrugBank ID DB00635
KEGG ID C07370
MeSH ID D011241
PubChem ID 5865
TTD Drug ID D0IL7L
NDC Product Code 51655-355; 70934-259; 60219-1705; 50090-3330; 71329-107; 80425-0069; 0527-2932; 63629-7917; 68071-2661; 61919-226; 0054-0018; 58118-0173; 50090-3336; 66267-173; 53002-3520; 59651-485; 61919-326; 42291-771; 75987-022; 71335-0464; 63629-2254; 63739-588; 70518-2676; 68071-4319; 60687-145; 67296-1183; 68071-5196; 53002-3250; 0603-5337; 53002-3092; 75987-021; 0054-8724; 51655-208; 68788-9309; 59651-489; 70954-060; 60219-1708; 69668-220; 51655-701; 66267-171; 55700-208; 63629-2264; 0527-2931; 63629-7753; 71335-1628; 64380-783; 60219-1707; 70954-057; 0591-5443; 42708-105; 66267-812; 0615-8395; 70934-218; 76420-067; 51655-726; 59746-175; 55700-209; 0527-2930; 71610-641; 50090-4428; 63629-8119; 63629-2260; 0527-2935; 53002-3252; 68071-4491; 42708-115; 0054-4742; 51407-360; 61919-235; 71335-0857; 80425-0106; 71335-1516; 67296-1419; 50090-2608; 82298-103; 50090-1990; 68071-5242; 68071-4685; 42291-769; 75987-020; 68788-8116; 68788-9551; 67296-1194; 71335-1915; 43063-866; 67544-399; 71205-407; 67296-0974; 68788-8108; 50090-4784; 70934-101; 0527-2934; 42708-136; 58118-5442; 60219-1706; 13672-031; 0591-5442; 51407-359; 63629-2261; 59651-487; 71335-0856; 63629-4562; 42291-768; 70518-1854; 63629-1587; 67296-0138; 70954-058; 55154-4949; 43063-703; 68071-2578; 68071-2304; 0054-9818; 71335-1220; 63629-2435; 70518-0306; 50090-1989; 71205-362; 71335-0623; 49999-028; 42291-770; 55700-203; 0054-8739; 61919-404; 70518-2703; 51407-355; 71335-1736; 71205-089; 68071-4903; 70518-2115; 80425-0105; 63187-243; 0054-3722; 70518-2314; 0054-9828; 68071-2445; 0395-8165; 50090-4785; 38779-0154; 63187-085; 70954-061; 50090-5657; 0143-9740; 68788-7692; 63187-037; 61919-108; 70518-2916; 50090-0439; 63629-1579; 71335-1285; 0904-6923; 61919-321; 42708-045; 0603-5336; 70882-117; 70518-0073; 68788-7281; 72189-275; 63187-807; 70954-059; 70518-1120; 67296-1203; 50090-1001; 50090-5814; 63629-2257; 60760-615; 67296-1065; 55154-4946; 59651-486; 67296-1083; 71335-0508; 68071-3143; 0143-9739; 50090-5660; 70934-831; 51552-0028; 63629-2259; 71335-1926; 60687-122; 70934-137; 64380-782; 43063-911; 0378-0640; 67296-1704; 55289-330; 71335-0651; 68071-2594; 50090-5656; 50090-0098; 71335-1780; 67296-0140; 50090-2532; 68071-5195; 0054-4728; 63629-2263; 50090-2786; 72189-246; 50090-3137; 42708-114; 54348-506; 68071-2500; 71329-105; 0615-0536; 0054-0019; 70518-2704; 71335-1524; 70934-096; 0904-7127; 68071-2209; 63187-997; 53002-3091; 71335-1629; 71335-1737; 63629-2258; 0527-2933; 55154-8130; 59651-484; 42291-727; 50090-0102; 51407-357; 59746-173; 68788-7637; 71335-0335; 0615-8307; 68071-2511; 68071-4862; 70934-699; 59746-172; 70934-674; 67296-1331; 68071-4691; 60760-255; 50090-1455; 71335-1525; 71205-460; 76420-068; 61919-373; 63629-2262; 59651-488; 0603-5339; 51407-358; 0603-5338; 76420-069; 70934-095; 68788-7752; 50090-3361; 0378-0642; 50090-1991; 71335-2051; 59746-171; 53002-0610; 0054-8740; 63187-020; 0615-3593; 67296-1755; 0603-5335; 72789-235; 0615-8306; 70518-3401; 71205-537; 70518-3138; 0615-8391; 64380-785; 60760-002; 70954-056; 57582-003; 68788-7372; 63187-300; 55154-4950; 68071-4850; 68071-2509; 0054-9817; 71205-239; 50090-5202; 0054-0017; 68071-1777; 55154-4938; 13672-033; 0591-5052; 71205-421; 71329-104; 61919-365; 45865-638; 0378-0641; 64380-835; 71329-108; 0143-9738; 70518-1561; 64380-784; 50090-5453; 71329-106; 60760-932; 70518-2138; 70518-3142; 63629-2255; 63629-2256; 13672-032; 60687-134; 63187-066; 63629-1605; 64958-0002; 50090-2789; 60760-715; 68788-6440; 50090-0097; 53002-3090; 70518-2675; 68071-1779; 66267-860; 66267-172; 43063-968; 63629-2434; 50090-5816; 71205-403; 43353-657; 51407-356; 0054-4741; 63629-8015; 67296-1767; 68788-8166; 67296-0247; 60722-1002; 45865-670; 70518-0307; 70518-0305; 71329-103; 49452-6000
Synonyms Prednisone | Dehydrocortisone | delta-Cortisone | Rectodelt | Prednison Hexal | Sterapred | Ultracorten | Winpred | Apo-Prednisone | Cortan | Cortancyl | Panafcort | Cutason | Decortin | Dacortin | Decortisyl | Deltasone | Encortone | Encorton | Enkortolon | Kortancyl | Liquid Pred | Meticorten | Orasone | Panasol | Predni Tablinen | Prednidib | Predniment | Prednison Acsis | Acsis, Prednison | Pronisone | Sone | Prednison Galen
Chemical Information
Molecular Formula C21H26O5
CAS Registry Number 53-03-2
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal adhesions12.02.03.006; 07.07.03.0010.000159%Not Available
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.000478%
Abdominal pain07.01.05.0020.001912%
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Abdominal tenderness07.01.05.0040.000040%Not Available
Abdominal wall abscess11.01.07.018; 07.19.02.0090.000040%Not Available
Abnormal faeces07.01.03.0010.000060%Not Available
Abnormal weight gain14.03.02.0100.000060%Not Available
Abortion spontaneous18.01.04.0010.000518%Not Available
Abscess11.01.08.0010.000259%Not Available
Acidosis14.01.03.0020.000100%
Acne23.02.01.0010.000199%Not Available
Acute febrile neutrophilic dermatosis01.02.01.006; 23.03.03.0330.000199%Not Available
Acute hepatic failure09.01.03.0010.000104%Not Available
Acute myeloid leukaemia16.01.05.001; 01.10.05.0010.000109%Not Available
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Acute promyelocytic leukaemia01.10.05.003; 16.01.05.0030.000021%Not Available
Acute pulmonary oedema22.01.03.005; 02.05.02.0040.000080%Not Available
Acute respiratory distress syndrome22.01.03.0010.000140%
Acute respiratory failure22.02.06.001; 14.01.04.0040.000047%Not Available
Adenocarcinoma16.16.01.0040.000010%Not Available
Adrenal atrophy14.11.01.030; 05.01.02.008--Not Available
Adrenal insufficiency14.11.01.004; 05.01.02.0010.000418%
Adrenal suppression14.11.01.005; 05.01.02.0020.000119%Not Available
Adrenocortical insufficiency acute14.11.01.020; 05.01.02.0050.000119%Not Available
Affective disorder19.04.04.0010.000080%Not Available
Ageusia07.14.03.003; 17.02.07.0010.000139%Not Available
Aggression19.05.01.001--Not Available
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