Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Copper
Drug ID BADD_D00529
Description Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. Copper is commonly used in contraceptive intrauterine devices (IUD) [L801].
Indications and Usage For use in the supplementation of total parenteral nutrition and in contraception with intrauterine devices [FDA Label] [L801].
Marketing Status Prescription; Discontinued
ATC Code Not Available
DrugBank ID DB09130
KEGG ID Not Available
MeSH ID D003300
PubChem ID 23978
TTD Drug ID D01WMJ
NDC Product Code 0220-1627; 0220-1624; 68428-349; 51285-204; 0220-1631; 62106-5020; 0220-1623; 0220-1635; 0220-1613; 59365-5128; 64117-958; 0220-1616; 0220-1651; 68428-140; 0220-1652; 0220-1636; 0220-1628; 0220-1648
Synonyms Copper | Copper-63 | Copper 63
Chemical Information
Molecular Formula Cu
CAS Registry Number 7440-50-8
SMILES [Cu]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Iron and trace metal metabolism disordersMetallothionein-1AP04731Not Available3967294; 2959538; 3662572
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abortion infected18.01.03.002; 11.01.10.015--Not Available
Anaemia01.03.02.001--
Back pain15.03.04.005--
Dermatitis allergic23.03.04.003; 10.01.03.014--Not Available
Dermatitis atopic10.01.04.004; 23.03.04.016--Not Available
Device expulsion27.01.01.002--Not Available
Dysmenorrhoea21.01.01.002--
Dyspareunia21.03.02.016; 19.08.05.004--
Ectopic pregnancy18.02.02.002--Not Available
Haemoglobin13.01.05.018--Not Available
Metrorrhagia21.01.01.006--Not Available
Muscle spasms15.05.03.004--
Neoplasm malignant16.16.01.001--Not Available
Nephropathy toxic20.05.03.002; 12.03.01.010--Not Available
Oligomenorrhoea21.01.02.004; 05.05.01.011--Not Available
Pain08.01.08.004--
Pregnancy18.08.02.004--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vaginal discharge21.08.02.002--
Vaginal infection21.14.02.002; 11.01.10.002--
Vaginal inflammation21.14.02.001--
Haemorrhage24.07.01.002--Not Available
Pelvic infection21.10.03.007; 11.01.08.026--
Urine output decreased13.13.03.001--
Adverse event08.06.01.010--Not Available
Pregnancy with contraceptive device18.08.01.002; 08.07.04.001--Not Available
Embedded device27.01.01.003--Not Available
Perforation08.01.03.058--Not Available
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