Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Macular oedema
ADR ID BADD_A02633
ADR Hierarchy
06      Eye disorders
06.04      Ocular infections, irritations and inflammations
06.04.06      Retinal, choroid and vitreous infections and inflammations
06.04.06.005      Macular oedema
Description Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90) | Fluid accumulation in the outer layer of the MACULA LUTEA at the center of the RETINA in a petaloid pattern where cystic spaces are formed and may lead to macular depressions or holes. [MeSH]
MedDRA Code 10025415
MeSH ID D008269
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Macula lutea oedema | Macular oedema | Macula lutea edema | Macular edema | Macular Edema | Edema, Macular | Irvine-Gass Syndrome | Irvine Gass Syndrome | Syndrome, Irvine-Gass | Cystoid Macular Edema, Postoperative | Macular Edema, Cystoid | Edema, Cystoid Macular | Cystoid Macular Dystrophy | Macular Dystrophy, Dominant Cystoid | Central Retinal Edema, Cystoid | Cystoid Macular Edema
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam--
BADD_D00274Bimatoprost0.002583%
BADD_D00284Bortezomib0.000533%
BADD_D00407Cefuroxime0.019797%
BADD_D00410Celecoxib0.000230%
BADD_D00474Cisplatin0.000533%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00551Cyclosporine0.000519%
BADD_D00589Dasatinib--
BADD_D00623Dexamethasone0.002403%
BADD_D00667Difluprednate--
BADD_D00680Dimethyl fumarate--
BADD_D00699Docetaxel0.000533%
BADD_D00774Entecavir0.014982%
BADD_D00899Fingolimod hydrochloride--
BADD_D00924Fluocinolone acetonide0.002297%
BADD_D00926Fluorescein--
BADD_D00981Gabapentin--
BADD_D01004Ganciclovir sodium--
BADD_D01006Gatifloxacin--
BADD_D01083Hydrochlorothiazide0.000044%
BADD_D01119Ibrutinib0.000799%
BADD_D01136Imatinib--
BADD_D01137Imatinib mesylate--
BADD_D01167Interferon alfa-2b--
BADD_D01251Latanoprost0.000563%
BADD_D01253Lenalidomide--
BADD_D01257Letrozole0.005537%
BADD_D01281Levonorgestrel--
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