Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methyl aminolevulinate hydrochloride
Drug ID BADD_D01424
Description Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Indications and Usage For topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).
Marketing Status Not Available
ATC Code L01XD03
DrugBank ID DB00992
KEGG ID D04988
MeSH ID C475457
PubChem ID 157921
TTD Drug ID Not Available
NDC Product Code 46016-7940
Synonyms methyl 5-aminolevulinate | MAOP cpd | methyl aminolaevulinate | Metvix
Chemical Information
Molecular Formula C6H12ClNO3
CAS Registry Number 79416-27-6
SMILES COC(=O)CCC(=O)CN.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Asthenia08.01.01.001--Not Available
Basal cell carcinoma23.08.02.001; 16.03.02.001--Not Available
Blister23.03.01.001; 12.01.06.002--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.003--Not Available
Discomfort08.01.08.003--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Eczema23.03.04.006--
Erythema23.03.06.001--Not Available
Eye disorder06.08.03.001--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Eyelid oedema10.01.05.001; 06.04.04.004; 23.04.01.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Infection11.01.08.002--Not Available
Keratitis06.04.02.002--
Macular oedema06.04.06.005--Not Available
Nausea07.01.07.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain08.01.08.004--
Pain of skin23.03.03.003--
Papule23.03.03.038--Not Available
Paraesthesia17.02.06.005--
Photosensitivity reaction23.03.09.003--
Pruritus23.03.12.001--
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